Results 61 to 70 of about 6,872 (253)
Determination of porin channel activity and evolution of targeting signals in plant peroxisomes [PDF]
, 2013 Peroxisomes are eukaryotic organelles traditionally known for their roles in fatty acid metabolism and generation and removal of hydrogen peroxide. Several new functions are being ascribed to these organelles with the help of genetic and proteomic based ...
Soni, Pradeep
core
Peroxisomes in parasitic protists
, 2016 Representatives of all major lineages of eukaryotes contain peroxisomes with similar morphology and mode of biogenesis, indicating a monophyletic origin of the organelles within the common ancestor of all eukaryotes.
Michels, Paul A.M. +5 more
core +1 more source
Peroxisome deficient invertebrate and vertebrate animal models
Frontiers in Physiology, 2013 Although peroxisomes are ubiquitous organelles in all animal species, their importance for the functioning of tissues and organs remains largely unresolved.
Paul P. Van Veldhoven, Myriam eBaes
doaj +1 more source
Advanced Science, EarlyView.Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie +12 more
wiley +1 more source
Yeast peroxisomes multiply by growth and division [PDF]
, 2007 Peroxisomes can arise de novo from the endoplasmic reticulum (ER) via a maturation process. Peroxisomes can also multiply by fission. We have investigated how these modes of multiplication contribute to peroxisome numbers in Saccharomyces cerevisiae and ...
Alison M. Motley +3 more
core +1 more source
Advanced Science, EarlyView.After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng +9 more
wiley +1 more source
Peroxisomes in pulmonate gastropods.
, 1977 Organelles with the morphologic characteristics of peroxisomes have been found in the cells of the kidney sac of two terrestrial pulmonate gastropods. Arion ater and Ariolimax columbianus. These peroxisomes appear in profile as circles or ellipses, 0.25
M E Beard, E Dannen
core +1 more source
Peroxisome biogenesis and peroxisome biogenesis disorders
FEBS Letters, 2000 Peroxisome assembly in mammals requires more than 15 genes. Two isoforms of the peroxisome targeting signal type 1 (PTS1) receptor, Pex5pS and Pex5pL, are identified in mammals. Pex5pS and Pex5pL bind PTS1 proteins. Pex5pL, but not Pex5pS, directly interacts with the PTS2 receptor, Pex7p, carrying its cargo PTS2 protein in the cytosol.
openaire +2 more sources
Journal of Lipid Research, 1993 Dihydroxyacetone phosphate acyl transferase (DHAP-AT), alkyl dihydroxyacetone phosphate synthase (alkyl-DHAP-synthase), and glycerol-3-phosphate acyltransferase (GPAT) activities were investigated under optimal assay conditions using highly purified ...
H Singh, K Beckman, A Poulos
doaj +1 more source
Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity
Advanced Science, EarlyView.This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao +10 more
wiley +1 more source