PLoS ONE, 2023 Peroxisomes are membrane-enclosed organelles with important roles in fatty acid breakdown, bile acid synthesis and biosynthesis of sterols and ether lipids. Defects in peroxisomes result in severe genetic diseases, such as Zellweger syndrome and neonatal
Tamara Somborac +7 more
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Rosy Beginnings: Studying Peroxisomes in Drosophila
Frontiers in Cell and Developmental Biology, 2020 Research using the fruit fly Drosophila melanogaster has traditionally focused on understanding how mutations affecting gene regulation or function affect processes linked to animal development.
C. Pridie +2 more
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Reduced peroxisomal import triggers peroxisomal retrograde signaling [PDF]
Cell Reports, 2021 Maintaining organelle function in the face of stress is known to involve organelle-specific retrograde signaling. Using Caenorhabditis elegans, we present evidence of the existence of such retrograde signaling for peroxisomes, which we define as the peroxisomal retrograde signaling (PRS).
Rackles, Elisabeth +10 more
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Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene [PDF]
, 2007 We aim to introduce the penicillin biosynthetic pathway into the methylotrophic yeast Hansenula polymorpha. To allow simultaneous expression of the multiple genes of the penicillin biosynthetic pathway, additional markers were required.
Gidijala, Loknath, +3 more
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A Peroxisomal Lon Protease and Peroxisome Degradation by Autophagy Play Key Roles in Vitality of Hansenula polymorpha Cells [PDF]
, 2007 In eukaryote cells various mechanisms exist that are responsible for the removal of non-functional proteins. Here we show that in the yeast Hansenula polymorpha (H.
Bener Aksam, Eda +5 more
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Degradation of plant peroxisomes by autophagy
Frontiers in Plant Science, 2014 Peroxisomes play a critical role in many metabolic pathways during the plant life cycle. It has been proposed that the transition between different types of peroxisomes involves the degradation of obsolete peroxisomal enzymes via proteolytic activities ...
Han Nim eLee, Jimi eKim, Taijoon eChung
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A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles [PDF]
, 2016 Survivin, the smallest member of the inhibitor of apoptosis protein family, plays a central role during mitosis and exerts a cytoprotective function. Survivin is highly expressed in most cancer types and contributes to multiple facets of carcinogenesis ...
Beghein, Els +5 more
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The impact of peroxisomes on cellular ageing and death
Frontiers in Oncology, 2012 Peroxisomes are ubiquitous eukaryotic organelles, which perform a plethora of functions including hydrogen peroxide metabolism and β-oxidation of fatty acids.
Selvambigai eManivannan +3 more
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A comparative study of peroxisomal structures in Hansenula polymorpha pex mutants [PDF]
, 2007 In a recent study, we performed a systematic genome analysis for the conservation of genes involved in peroxisome biogenesis (PEX genes) in various fungi.
Klei, Ida J. van der, +3 more
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Research progress on the metabolic functions and protein compositions of plant peroxisomes
浙江大学学报. 农业与生命科学版Peroxisomes are multifunctional organelles that are ubiquitous in eukaryotes. In plants, peroxisomes have very diverse functions in primary and secondary metabolisms and play important roles in plant growth and development as well as in stress response ...
ZHANG Yuchan, DAI Huaxin, PAN Ronghui
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