Results 51 to 60 of about 42,473 (314)
Melatonin-Nrf2 Signaling Activates Peroxisomal Activities in Porcine Cumulus Cell-Oocyte Complexes
Antioxidants, 2020 Melatonin and Nrf2 signaling synergistically improve mammalian oocyte maturation and embryonic development. Furthermore, previous studies have suggested an interplay between peroxisomes and Nrf2 signaling in cells, but it is still unclear whether ...
Eui Hyun Kim +3 more
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Peroxisomes in intracellular cholesterol transport: from basic physiology to brain pathology
Exploration of Neuroprotective Therapy, 2021 Peroxisomes are actively involved in the metabolism of various lipids including fatty acids, ether phospholipids, bile acids as well as the processing of reactive oxygen and nitrogen species.
Jian Xiao, Bao-Liang Song, Jie Luo
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The Evolutionary Origin of Peroxisomes: An ER-Peroxisome Connection [PDF]
Molecular Biology and Evolution, 2006 The peroxisome is an essential eukaryotic organelle, crucial for lipid metabolism and free radical detoxification, development, differentiation, and morphogenesis from yeasts to humans. Loss of peroxisomes invariably leads to fatal peroxisome biogenesis disorders in man.
Schlüter, Agatha +5 more
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FEBS Open Bio, EarlyView.Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto +5 more
wiley +1 more source
Peroxisome deficient invertebrate and vertebrate animal models
Frontiers in Physiology, 2013 Although peroxisomes are ubiquitous organelles in all animal species, their importance for the functioning of tissues and organs remains largely unresolved.
Paul P. Van Veldhoven, Myriam eBaes
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Pediatric Neurology Briefs, 1988 Generalized peroxisomal disorders are classified in three main groups in a review article from the Kennedy Institute and the Departments of Neurology and Pediatrics, Johns Hopkins University, 707 N. Broadway, Baltimore, MD.
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FEBS Open Bio, EarlyView.Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová +11 more
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Peroxisomal-PEX5 Controls Fasting-Induced Lipolysis
Contact, 2020 Lipid droplets (LDs) are dynamic subcellular organelles which play critical roles for lipid homeostasis upon change of nutritional state. Although several organelles such as mitochondria and peroxisomes are involved in lipid metabolism, physiological ...
Ji Seul Han, Kyung Hee Han, Jae Bum Kim
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FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Dynamics of Peroxisome Homeostasis and Its Role in Stress Response and Signaling in Plants
Frontiers in Plant Science, 2019 Peroxisomes play vital roles in plant growth, development, and environmental stress response. During plant development and in response to environmental stresses, the number and morphology of peroxisomes are dynamically regulated to maintain peroxisome ...
Tong Su +3 more
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