Results 51 to 60 of about 3,869,667 (308)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Osobne i organizacijske radne vrijednosti kao prediktori odanosti organizaciji

Psychological Topics, 2016
Cilj je provedenog istraživanja bio ispitati u kojoj mjeri osobne i percipirane organizacijske vrijednosti kao i njihova interakcija pridonose objašnjenju varijance odanosti organizaciji i njezinih komponenti, a nakon kontrole dužine radnog staža u ...
Nada Krapić, Sanja Barić
doaj  

Sowing the seeds of happiness, personal values, and creative behavior: The role of CSR perception in hospitality services

Acta Psychologica
Employee creative behavior (ECB) is vital for innovation and competitiveness in hospitality firms, yet its antecedents remain underexplored in non-Western contexts.
Jun Ye
doaj   +1 more source

Piloting PIVOT: The Professional Identity and Values Organisation Tool [PDF]

, 2009
PIVOT was piloted between March and September 2008 with a small number of tutors and students on the social work programme in one region in England. The project involved the creation and trialling of a suite of reflective activities based upon Personal ...
Cooper, Barry, Pickering, Maggie
core  

The Social Nature of Individual Self-Identity: Akan and Narrative Conceptions of Personhood [PDF]

, 2015
Marya Schechtman has given us reasons to think that there are different questions that compose personal identity. On the one hand, there is the question of reidentification, which concerns what makes a person the same person through different time-slices.
Barnes, Corey L.
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

A cluster-analytic study of personal values, work orientations, and job satisfaction among young adults in northern Italy

Discover Psychology
This study, drawing on the Multidimensional Model of Work Orientations, investigates the relationship between personal values, the meanings attributed to work (work orientations), and job satisfaction in a sample of young Italian adults.
Ferdinando Toscano, Salvatore Zappalà
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Making things happen : a model of proactive motivation [PDF]

, 2010
Being proactive is about making things happen, anticipating and preventing problems, and seizing opportunities. It involves self-initiated efforts to bring about change in the work environment and/or oneself to achieve a different future.
Aragon-Correa, J.A., Ashford, S.J., Ashford, S.J., Ashford, S.J., Ashford, S.J., Ashford, S.J., Ashforth, B.E., Aspinwall, L.G., Aspinwall, L.G., Axtell, C.M., Bandura, A., Bandura, A., Bateman, T.S., Belschak, F.D., Berg, J.M., Bindl, U.K., Bindl, U.K., Bindl, U.K., Binnewies, C., Bledow, R., Brockner, J., Brown, D.J., Burris, E.R., Carnevale, P.J.D., Carver, C.S., Chan, D., Chen, G., Choi, J.N., Crant, J.M., Csikszentmihalyi, M., Damasio, A.R., Deci, E.L., Deci, E.L., Deluga, R.J., Dutton, J.E., Dutton, J.E., Dutton, J.E., Dweck, C.S., Eccles, J.S., Eccles, J.S., Erdogan, B., Fay, D., Fredrickson, B.L., Frese, M., Frese, M., Frese, M., Frijda, N.H., Fuller, B., Jr., Fuller, B., Jr., Gagné, M., Gervey, B., Grant, A.M., Grant, A.M., Grant, A.M., Griffin, M.A., Griffin, M.A., Hobfoll, S.E., Howell, J.M., Ilies, R., Isen, A.M., Isen, A.M., Janssen, O., Johnson, E.C., Kanfer, R., Kanfer, R., Kanfer, R., Karoline Strauss, Kirkman, B.L., Koestner, R., Kraiger, K., Lakhani, K.R., Leary, M.R., LePine, J.A., Liberman, N., Locke, E.A., Major, D.A., Massimini, F., McAllister, D.J., Mischel, W., Morrison, E.W., Oettingen, G., Ohly, S., Ohly, S., Oyserman, D., Parker, S.K., Parker, S.K., Parker, S.K., Parker, S.K., Parker, S.K., Parker, S.K., Parker, S.K., Parker, S.K., Raabe, B., Rank, J., Rank, J., Rank, J., Rigby, C.S., Roberts, B.W., Rousseau, D.M., Rupp, D.E., Russell, J.A., Salanova, M., Schwartz, S.H., Scott, S.G., Seibert, S.E., Seo, M.-G., Seo, M.-G., Sharon K. Parker, Sheldon, K.M., Sonnentag, S., Strathman, A., Strauss, K., Strauss, K., Tett, R.P., Thompson, J.A., Tsai, W.C., Tuckey, M., Uta K. Bindl, van Knippenberg, D., VandeWalle, D., Vroom, V.H., Wagner, S.H., Wegener, D.T., Wegner, D.M., Williams, H., Wrzesniewski, A., Wrzesniewski, A.   +126 more
core   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source