Results 51 to 60 of about 63,438 (288)

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Personalized Nutrition: Making It Happen

, 2019
Personalized nutrition allows individual variation in dietary, lifestyle, anthropometric, phenotypic, and/or genomic information to be considered when giving dietary advice.
Abrahams, Mariette, Bryant, Eleanor, Eleanor Bryant, Mariette Abrahams, Bruno M.P.M. Oliveira, Gibney, Eileen R., Oliveira, Bruno M.P.M., Eileen R. Gibney, Rankin, Audrey, Rui Poínhos, Audrey Rankin, Stewart-Knox, Barbara, Barbara Stewart-Knox, Poínhos, Rui   +13 more
core   +1 more source

Personalized Nutrition in the Management of Female Infertility: New Insights on Chronic Low-Grade Inflammation

, 2022
Increasing evidence on the significance of nutrition in reproduction is emerging from both animal and human studies, suggesting a mutual association between nutrition and female fertility.
Carla Tatone, Alberto Vaiarelli, Gennarelli, Gianluca, Nicolò Ubaldi, Tatone, Carla, Stuppia, Liborio, Franzago, Marica, Verdone, Giulia, Marica Franzago, Rienzi, Laura, Laura Rienzi, Allori, Mariachiara, Vaiarelli, Alberto, Giulia Verdone, Filippo Maria Ubaldi, Danilo Cimadomo, Gianluca Gennarelli, Liborio Stuppia, Mariachiara Allori, Cimadomo, Danilo, Ubaldi, Nicolò, Ubaldi, Filippo Maria, Fabozzi, Gemma, Gemma Fabozzi   +23 more
core   +1 more source

A system approach to simulation of individual food products

Теория и практика переработки мяса, 2020
There is no doubt that the further development in the field of nutrition is linked with personalization. Nutrition management with account for metabolism plays a key role in health strengthening and prevention of human diseases.
A. B. Lisitsyn, I. M. Chernukha, M. A. Nikitina   +2 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Nutrition-Related N-of-1 Studies Warrant Further Research to Provide Evidence for Dietitians to Practice Personalized (Precision) Medical Nutrition Therapy: A Systematic Review

, 2023
N-of-1 trials provide a higher level of evidence than randomized controlled trials for determining which treatment works best for an individual, and the design readily accommodates testing of personalized nutrition.
Margaret Allman-Farinelli, Eric Hekler, Tiffany Vuong, Brianna Boljevac   +3 more
core   +1 more source

Associations of Rheumatoid Arthritis Disease Activity With Frailty Over Five Years of Follow‐up

Arthritis Care &Research, EarlyView.
Objective To evaluate whether rheumatoid arthritis (RA) disease activity is associated with frailty both in cross‐section and longitudinally. Methods Participants within the Veterans Affairs Rheumatoid Arthritis (VARA) registry enrolled from 2003 to 2022 were included.
Courtney N. Loecker, Yangyuna Yang, Punyasha Roul, Aaron Baraff, Myra S. Schmaderer, Lani Zimmerman, Kaleb Michaud, Namrata Singh, Grant W. Cannon, Gary Kunkel, Ted R. Mikuls, Ariela R. Orkaby, Joshua F. Baker, Bryant R. England, Katherine D. Wysham   +14 more
wiley   +1 more source

Ethical Issues raised by Personalized Nutrition based on Genetic Information [Elektronisk resurs]

, 2006
Four principles are taken as basis for the ethical analysis: autonomy, nonmaleficence, beneficence, and justice. Health is understood as a limited aspect of wellbeing.
Görman, Ulf,, Lund University.
core   +1 more source

Obesity Subtypes and Longitudinal Trajectories of Function Over Seven Years of Follow‐Up: Data From the Multicenter Osteoarthritis Study

Arthritis Care &Research, EarlyView.
Objective Obesity, defined by body mass index (BMI) ≥30 kg/m2, is a risk factor for functional limitations in people with knee osteoarthritis (OA). However, function varies among such individuals. Our objective was to evaluate the implications of obesity subtypes on longitudinal patterns of physical functioning in people with or at risk for knee OA ...
Kristine Godziuk, Sarah Tilley, Michael LaValley, Michael C. Nevitt, Cora E. Lewis, James C. Torner, Tuhina Neogi, for the Multicenter Osteoarthritis Study Group   +7 more
wiley   +1 more source