Results 41 to 50 of about 59,116 (247)
Getting Personal About Nutrition [PDF]
Trends in Molecular Medicine, 2016 Nutritional guidelines for maintaining healthy blood glucose levels are commonly portrayed as universally applicable. However, a new study now demonstrates that the impact of each food on blood glucose varies dramatically across individuals and largely depends on personal characteristics and gut microbiome properties, laying the foundation for the ...
Cecilia, Noecker, Elhanan, Borenstein
openaire +2 more sources
Stance4Health Nutritional APP: A Path to Personalized Smart Nutrition
Nutrients, 2022 Access to good nutritional health is one of the principal objectives of current society. Several e-services offer dietary advice. However, multifactorial and more individualized nutritional recommendations should be developed to recommend healthy menus according to the specific user’s needs.
Daniel Hinojosa-Nogueira +6 more
openaire +4 more sources
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
A system approach to simulation of individual food products
Теория и практика переработки мяса, 2020 There is no doubt that the further development in the field of nutrition is linked with personalization. Nutrition management with account for metabolism plays a key role in health strengthening and prevention of human diseases.
A. B. Lisitsyn +2 more
doaj +1 more source
Breast-feeding as ‘personalized nutrition’ [PDF]
European Journal of Clinical Nutrition, 2018 Health benefits of breast-feeding have been recognised since antiquity [1], and yet with every passing decade, our scientific understanding of breast-feeding as a mode of nutrition seems to accelerate rather than reach a ‘final plateau’. We already have compelling evidence that it matters, yet we also have much to discover about how exactly breast ...
openaire +2 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Aging and Cancer, EarlyView.This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Communications Biology, 2022 A genome-wide association study in a Chinese population identifies SNPs associated with serum copper levels. Mendelian randomization analysis reveals causal effects on multiple human phenotypes in East Asian and European populations.
Wenjun Yang +11 more
doaj +1 more source