Results 111 to 120 of about 1,146,068 (304)

Rapid Decentralized Prostate Cancer Risk Stratification by Portable Liquid Biopsy Analysis within a Clinical Biosensor Validation Framework

open access: yesAdvanced Science, EarlyView.
In this work, we showcased two significant scientific advances in (i) developing a portable biosensor technology for rapid decentralized prostate cancer urinary biomarker testing and reporting, with superior performance to current clinical testing practice; and (ii) proposing a clinical validation framework (for our biosensor development) which can be ...
Kevin M. Koo   +14 more
wiley   +1 more source

Construction of PANoptosis‐Inhibiting Carbonized Polymer Dots via Machine Learning Potential for Mitigating Chemodrug‐Induced Nephrotoxicity

open access: yesAdvanced Science, EarlyView.
An enhanced sampling method is developed for molecular dynamics based on trained machine learning force fields to guide the construction of PANoptosis‐inhibiting carbonized polymer dots (Lu‐CDs) derived from a flavonoid compound for treating chemodrug‐induced nephrotoxicity.
Xinchen Liu   +8 more
wiley   +1 more source

Parliament membership during the single-party system in Turkey (1925-1945) [PDF]

open access: yes, 2005
The official legitimization of the single-party regime in Turkey lay with Parliament, which, as a representative of the people, controlled the legislature, the executive and the judiciary. However, the parliamentary period after 1925 was highlighted by a
Kocak, Cemil, Koçak, Cemil
core  

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

open access: yesAdvanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li   +19 more
wiley   +1 more source

Introduction to SIMRAND: Simulation of research and development project [PDF]

open access: yes
SIMRAND: SIMulation of Research ANd Development Projects is a methodology developed to aid the engineering and management decision process in the selection of the optimal set of systems or tasks to be funded on a research and development project.
Miles, R. F., Jr.
core   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

open access: yesAdvanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi   +7 more
wiley   +1 more source

METODOLOGÍA PARA UBICAR ESTUDIANTES EN ROLES DEL PROCESO DE DESARROLLO DE SOFTWARE / METHODOLOGY FOR PLACING STUDENTS IN ROLES OF THE SOFTWARE DEVELOPMENT PROCESS

open access: yesRevista Científica de Ingeniería Industrial, 2013
La Universidad de las Ciencias Informáticas tiene la responsabilidad de la formación de profesionales de la informática, así como la participación directa en el desarrollo de proyectos de informatización nacional y compromisos de exportación.
Lizandra Arza-Pérez   +2 more
doaj  

Tenth report to Committee on Selection of Personnel, American Institute of Accountants, April 15, 1947. [PDF]

open access: yes, 1947
https://egrove.olemiss.edu/aicpa_assoc/2635/thumbnail ...
American Institute of Accountants. Committee of Selection of Personnel
core   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang   +12 more
wiley   +1 more source

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