Results 1 to 10 of about 189 (129)

Protein Persulfidation in Plants: Function and Mechanism [PDF]

open access: yesAntioxidants, 2021
As an endogenous gaseous transmitter, the function of hydrogen sulfide (H2S) has been extensively studied in plants. Once synthesized, H2S may be involved in almost all life processes of plants.
Weibiao Liao, Liao Weibiao
exaly   +5 more sources

The Role of Protein Persulfidation in Brain Aging and Neurodegeneration [PDF]

open access: yesFrontiers in Aging Neuroscience, 2021
Hydrogen sulfide (H2S), originally considered a toxic gas, is now a recognized gasotransmitter. Numerous studies have revealed the role of H2S as a redox signaling molecule that controls important physiological/pathophysiological functions.
Dunja Petrovic   +3 more
doaj   +3 more sources

Proteome Dynamics of Persulfidation in Leaf Tissue under Light/Dark Conditions and Carbon Deprivation

open access: yesAntioxidants, 2023
Hydrogen sulfide (H2S) acts as a signaling molecule in plants, bacteria, and mammals, regulating various physiological and pathological processes.
Ana Jurado-Flores   +2 more
exaly   +3 more sources

Emerging Chemical Biology of Protein Persulfidation

open access: yesAntioxidants and Redox Signaling, 2023
Significance: Protein persulfidation (the formation of RSSH), an evolutionarily conserved oxidative posttranslational modification in which thiol groups in cysteine residues are converted into persulfides, has emerged as one of the main mechanisms through which hydrogen sulfide (H
Thibaut Vignane, Miloš R Filipovic
exaly   +3 more sources

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science
Targeting transcriptional regulatory complexes represents a promising strategy for activating thermogenic fat and treating obesity. In this study, we focused on identifying critical, specific metabolic pathways enriched during brown adipocyte ...
Xin Peng   +8 more
doaj   +2 more sources

Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging

open access: yesRedox Biology
Protein persulfidation is a significant post-translational modification that involves addition of a sulfur atom to the cysteine thiol group and is facilitated by sulfide species.
Ilka Wittig   +2 more
exaly   +3 more sources

Dual Roles of Reducing Systems in Protein Persulfidation and Depersulfidation

open access: yesAntioxidants
The oxidative modification of specific cysteine residues to persulfides is thought to be the main way by which hydrogen sulfide (H2S) exerts its biological and signaling functions. Therefore, protein persulfidation represents an important thiol-switching
Zhichao Liu   +2 more
exaly   +3 more sources

Protocol for using organic persulfides to measure the chemical reactivity of persulfide sensors

open access: yesSTAR Protocols, 2022
Hydrogen sulfide (H2S) and downstream reactive sulfur species (RSS), including organic persulfides, protect bacterial cells against diverse oxidative stressors. Specialized dithiol-based transcriptional repressors sense persulfides directly to control cellular H2S/RSS and avoid toxicity.
Joseph N. Fakhoury   +2 more
openaire   +4 more sources

Proteomics Profiling of S-sulfurated Proteins in Acinetobacter baumannii

open access: yesBio-Protocol, 2021
Hydrogen sulfide (H2S) is emerging as an important modulator in bacterial cytoprotection against the host immune response in infected animals, which may well be attributed to downstream highly oxidized sulfur species, termed reactive sulfur species (RSS),
Brenna Walsh, David Giedroc
doaj   +1 more source

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response.

open access: yesPLoS Biology, 2021
Aspergillus fumigatus is a human fungal pathogen that can cause devastating pulmonary infections, termed "aspergilloses," in individuals suffering immune imbalances or underlying lung conditions.
Monica Sueiro-Olivares   +17 more
doaj   +1 more source

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