Results 31 to 40 of about 444 (152)

Persulfidation is the mechanism underlying sulfide-signaling of autophagy [PDF]

Autophagy, 2021
In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H2S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved
Gotor, Cecilia, Aroca, Angeles, Romero, Luis C.   +2 more
openaire   +5 more sources

Label-Free Quantitative Proteomic Analysis of Nitrogen Starvation in Arabidopsis Root Reveals New Aspects of H₂S Signaling by Protein Persulfidation

Antioxidants, 2021
Hydrogen sulfide (H2S)-mediated signaling pathways regulate many physiological and pathophysiological processes in mammalian and plant systems.
Ana Jurado-Flores, Luis C. Romero, Cecilia Gotor   +2 more
doaj   +1 more source

Thioredoxin Network in Plant Mitochondria: Cysteine S-Posttranslational Modifications and Stress Conditions

Frontiers in Plant Science, 2020
Plants are sessile organisms presenting different adaptation mechanisms that allow their survival under adverse situations. Among them, reactive oxygen and nitrogen species (ROS, RNS) and H2S are emerging as components not only of cell development and ...
María Carmen Martí, Ana Jiménez, Francisca Sevilla   +2 more
doaj   +1 more source

Abscisic Acid-Triggered Persulfidation of Cysteine Protease ATG4 Mediates Regulation of Autophagy by Sulfide [PDF]

, 2020
48 Pags.- 10 Figs. The definitive version, with suppl mat., is available at: http://www.plantcell.org/Hydrogen sulfide is a signaling molecule that regulates essential processes in plants, such as autophagy.
Laureano-Marín, A.M., Pérez-Pérez, M.E., Yruela, I., Crespo, José L., Ángeles Aroca,, Inmaculada Yruela,, Aroca, Á., Laureano-Marín, Ana M., Cecilia Gotor, Aroca Aguilar, Ángeles, Jurado-Flores, Ana, Gotor Martínez, Cecilia, Ana M. Laureano-Marín,, Pérez-Pérez, M. Esther, M. Esther Pérez-Pérez,, Ana Jurado-Flores,, Pérez Pérez, Maria Esther, Laureano Marín, Ana María, Crespo, J.L., Romero González, Luis Carlos, Inmaculada Moreno,, Jurado-Flores, A., Moreno, I., Yruela Guerrero, Inmaculada, Gotor, Cecilia, José L. Crespo,, Romero, Luis C., Moreno, Inmaculada, Luis C. Romero,, Moreno González, María Inmaculada, Romero, L.C., Gotor, C., Jurado Flores, Ana, Crespo González, José Luis, Aroca, Ángeles   +34 more
core   +1 more source

Oral Administration of Glutathione Trisulfide Increases Reactive Sulfur Levels in Dorsal Root Ganglion and Ameliorates Paclitaxel-Induced Peripheral Neuropathy in Mice

Antioxidants, 2022
Peripheral neuropathy is a dose-limiting side effect of chemotherapy with paclitaxel. Paclitaxel-induced peripheral neuropathy (PIPN) is typically characterized by a predominantly sensory neuropathy presenting with allodynia, hyperalgesia and spontaneous
Mariko Ezaka, Eizo Marutani, Yusuke Miyazaki, Eiki Kanemaru, Martin K. Selig, Sophie L. Boerboom, Katrina F. Ostrom, Anat Stemmer-Rachamimov, Donald B. Bloch, Gary J. Brenner, Etsuo Ohshima, Fumito Ichinose   +11 more
doaj   +1 more source

Biosynthesis and Reactivity of Cysteine Persulfides in Signaling [PDF]

Journal of the American Chemical Society, 2015
Hydrogen sulfide (H2S) elicits pleiotropic physiological effects ranging from modulation of cardiovascular to CNS functions. A dominant method for transmission of sulfide-based signals is via posttranslational modification of reactive cysteine thiols to persulfides. However, the source of the persulfide donor and whether its relationship to H2S is as a
Pramod K, Yadav, Michael, Martinov, Victor, Vitvitsky, Javier, Seravalli, Rudolf, Wedmann, Milos R, Filipovic, Ruma, Banerjee   +6 more
openaire   +2 more sources

Nitrated Nucleotides: New Players in Signaling Pathways of Reactive Nitrogen and Oxygen Species in Plants

Frontiers in Plant Science, 2020
Nitration of diverse biomolecules, including proteins, lipids and nucleic acid, by reactive nitrogen species represents one of the key mechanisms mediating nitric oxide (NO) biological activity across all types of organisms.
Marek Petřivalský, Lenka Luhová
doaj   +1 more source

Persulfidation of Nitrate Reductase 2 Is Involved in l-Cysteine Desulfhydrase-Regulated Rice Drought Tolerance

, 2021
Hydrogen sulfide (H2S) is an important signaling molecule that regulates diverse cellular signaling pathways through persulfidation. Our previous study revealed that H2S is involved in the improvement of rice drought tolerance. However, the corresponding
Xingxing Yuan, Ye Su, Feng Zhang, Yanjie Xie, Heng Zhou, Wenxue Guan, Ying Zhou   +6 more
core   +1 more source

Synthetic Motifs for Understanding Lewis Acid Interactions with Persulfides and Thioselenides

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
Using isolated dichalcogenides as precursors, we report the synthesis, characterization, and reactivity of Zn persulfide and thioselenide complexes. 77Se NMR shows distinct impacts to electronic structure and reactivity between different thioselenides coordinated to different Lewis acids.
Keyan Li, Addison J. Sattler, Lev N. Zakharov, Michael D. Pluth   +3 more
wiley   +2 more sources

New role for thioredoxins in plants: Implication of TRXo1 in protein depersulfidation

Redox Biology
Persulfidation, a posttranslational modification of cysteines to persulfides, is the best characterized molecular mechanism of H2S signaling. This study is focused on new functions for thioredoxins (TRXs) in plants beyond those of thiol disulfide (S–S ...
Sabrina De Brasi-Velasco, Angeles Aroca, Luis C. Romero, Cecilia Gotor, Francisca Sevilla, Ana Jiménez   +5 more
doaj   +1 more source