Results 51 to 60 of about 444 (152)
Über Persulfide von Aldehyden [PDF]
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Bugge, Günther, Bloch, Ignaz
openaire +1 more source
A novel persulfide detection method reveals protein persulfide- and polysulfide-reducing functions of thioredoxin and glutathione systems [PDF]
Protein Persulfide Detection Protocol reveals vital roles for thioredoxin and glutathione systems in maintaining sulfane sulfur homeostasis in cells and in vivo.
Éva Dóka +11 more
openaire +4 more sources
Hypoxia sensing requires H2S-dependent persulfidation of olfactory receptor 78 [PDF]
Oxygen (O2) sensing by the carotid body is critical for maintaining cardiorespiratory homeostasis during hypoxia. Hydrogen sulfide (H2S) signaling is implicated in carotid body activation by low O2. Here, we show that persulfidation of olfactory receptor
Ganesh K. Kumar +21 more
core +1 more source
Acute inflammatory responses often involve the production of reactive oxygen and nitrogen species by innate immune cells, particularly macrophages. How activated macrophages protect themselves in the face of oxidative-inflammatory stress remains a long ...
Talal Salti +4 more
doaj +1 more source
Novel roles of sulfur metabolism in stress‐controlled stomata aperture regulation
Summary Stomatal closure allows plants to conserve water by reducing transpiration during drought. Surprisingly, the assimilation of the macronutrient sulfur is intimately connected to the drought stress response. This Tansley insight will only briefly touch on the general impact of sulfate assimilation on the production of drought‐response metabolites.
Sheng‐Kai Sun +2 more
wiley +1 more source
Linking Superoxide Production and Scavenging in Plant Development
ABSTRACT Due to their strong oxidizing potential, rapid membrane permeability, and high reactivity, reactive oxygen species (ROS) play essential roles in plant development and stress responses. Superoxide (O2•‐) is a primary product of molecular oxygen reduction and a crucial source of hydrogen peroxide, representing a ROS species of substantial ...
Jan Řehák +3 more
wiley +1 more source
Protein persulfidation in plants : Mechanisms and functions beyond a simple stress response [PDF]
Posttranslational modifications (PTMs) can modulate the activity, localization and interactions of proteins and (re)define their biological function. Understanding how changing environments can alter cellular processes thus requires detailed knowledge ...
Moseler, Anna +2 more
core +1 more source
Dietary restriction (DR) can increase protein persulfidation but the tissue specificity of this process is not well understood. Here, the authors compare organ-specific protein persulfidomes in young and aged mice under DR, and show that DR-dependent ...
Nazmin Bithi +8 more
doaj +1 more source
Lifespan‐Extending Endogenous Metabolites
Endogenous metabolites act as mediators of longevity by modulating conserved cellular pathways. We summarize mechanistic evidence linking specific metabolites to lifespan and healthspan benefits across model systems, with discussion of clinical evidence, translational opportunities, and remaining knowledge gaps.
Yizhou Jiang, Jing‐Dong J. Han
wiley +1 more source
Polysulfides promote ATF6 oligomerization via persulfidation to modulate ER stress responses
ATF6 is a UPR sensor regulated by redox modification of luminal cysteine residues. Although polysulfides modulate proteins through cysteine persulfidation, their effect on ATF6 has been unclear.
Shin Koike +2 more
doaj +1 more source

