Results 81 to 90 of about 444 (152)

The Role of Sulfide in Reticulophagy through the Regulation of ATG18a by Persulfidation

, 2020
Autophagy is a major catabolic process in eukaryotic cells to degrade dysfunctional or unnecessary cellular components. It has conserved functions in development, cellular homeostasis, and stress responses from yeast to plants and mammals.
Angeles Aroca, Diane Bassham
core   +1 more source

The Role of Ferroptosis in Diabetes Pathogenesis: Therapeutic Implications of Hydrogen Sulfide and Its Reactive Metabolites

Antioxidants
Ferroptosis, a regulated form of cell death characterized by iron-dependent lipid peroxidation, emerged as an important contributor to the pathogenesis of diabetes and its complications.
Vesna Otasevic, Milica Markelic, Marko Miler, Nevena Savic, Ksenija Velickovic, Andjelija Gudelj, Ilijana Grigorov, Ana Stancic   +7 more
doaj   +1 more source

Persulfidation alters gene regulatory programs and promotes endothelial specification

Redox Biology
Endogenously generated sulfides are conserved among species and tissues and exert multiple effects through diverse mechanisms. Although sulfides have been linked to cell fates, their role in pluripotent stem cell commitment remains unknown.
Janina Wittig, Ran Xu, Fredy Delgado Lagos, Maria-Kyriaki Drekolia, Boran Zhang, Ioannis Theodorou, Yunyun Chen, Yali Du, Lavanya Gupta, Cui Hanyu, Li Yuanyuan, Cheng Bo, Stefan Günther, Ilka Wittig, Roxana Ola, Jiong Hu, Sofia-Iris Bibli   +16 more
doaj   +1 more source

The Activity of YCA1 Metacaspase Is Regulated by Reactive Sulfane Sulfur via Persulfidation in Saccharomyces cerevisiae

Antioxidants
YCA1, the only metacaspase in Saccharomyces cerevisiae, plays important roles in the regulation of chronological lifespan, apoptosis, and cytokinesis. YCA1 has protein hydrolase activity and functions by cleaving itself and target proteins.
Qingda Wang, Xiaokun Zhang, Zhuang Du, Honglei Liu, Yongzhen Xia, Luying Xun, Huaiwei Liu   +6 more
doaj   +1 more source

Plant H2S and Transcription Factors (TFs) Interactions: Unexplored Area

Frontiers in Bioscience-Landmark
Plant hydrogen sulfide (H2S) metabolism has garnered noteworthy attention due to its role in regulating many plant processes. The primary mechanism by which H2S exerts its signaling functions is through its reversible interaction with thiol groups on ...
Francisco J Corpas
doaj   +1 more source

Supplementary material for the article: Lemon extract reduces hepatic oxidative stress and persulfidation levels by upregulating Nrf2 and Trx1 expression in old rats

, 2023
This dataset is a supplementary document of the research article: Lemon extract reduces hepatic oxidative stress and persulfidation levels by upregulating Nrf2 and Trx1 expression in old rats.
Živanović, Jasmina, Miler, Marko
core  

Mining proteomes for zinc finger persulfidation

RSC Chemical Biology
A meta-analysis of 22 persulfide-specific proteomics datasets reveals widespread persulfidation of zinc finger proteins across various species, highlighting the role of persulfidation as an important post-translational modification.
Haoju Li, Andrew T. Stoltzfus, Sarah L. J. Michel   +2 more
openaire   +2 more sources

The Elucidation of Hydrogen Sulfide Signalling Through Persulfidation

, 2019
Le sulfure d’hydrogène (H2S), auparavant considéré comme un gaz toxique, est aujourd’hui reconnu comme gazotransmetteur. De nombreuses études ont révélé le rôle de l’H2S en tant que molécule de signalisation redox contrôlant d’importantes fonctions ...
KOUROUSSIS, Emilia
core  

Table_1_Ethylene-Induced Hydrogen Sulfide Negatively Regulates Ethylene Biosynthesis by Persulfidation of ACO in Tomato Under Osmotic Stress.DOC

, 2018
A number of recent studies identified hydrogen sulfide (H2S) as an important signal in plant development and adaptation to environmental stress. H2S has been proven to participate in ethylene-induced stomatal closure, but how the signaling pathways of ...
Juan Wang (115708), Meijuan Ren (5865158), Xiaofeng Wang (119575), Wei Shi (68167), Dan Liu (108669), Honglei Jia (5865155), Sisi Chen (166395), Jun Yang (2084), Johannes Liesche (3275763), Jisheng Li (155989), Cong Shi (844412)   +10 more
core   +1 more source

Cysteine Thiol-Based Oxidative Post-Translational Modifications Fine-Tune Protein Functions in Plants

Agronomy
Post-translational modification is a prerequisite for the functions of intracellular proteins. Thiol-based oxidative post-translational modifications (OxiPTMs) mainly include S-sulfenylation, S-nitrosation, persulfidation, and S-glutathionylation ...
Hongxin Li, Xiaoyun Wang, Ying Liu, Peiyang Zhang, Fuyuan Chen, Na Zhang, Bing Zhao, Yang-Dong Guo   +7 more
doaj   +1 more source