Results 101 to 110 of about 444 (152)

Naturally aged rats, characterized by persulfidation decline, provide an adequate translational preclinical model for BPH: A hypothesis

Benign prostatic hyperplasia (BPH) is a prevalent age-related disorder characterized by progressive prostate enlargement. Current preclinical models fail to replicate decline in persulfidation and chronic oxidative stress, inflammation, and cellular ...
Živanović, Jasmina, Mijajlović, Vladimir, Miler, Marko, Vukojević, Milica, Filipović, Branko, Mojić, Marija, Ajdžanović, Vladimir   +6 more
core   +1 more source

Profiling the landscape of cysteine posttranslational modifications in brain aging and neurodegeneration

Neurotherapeutics
Cysteine residues occupy a unique position in the proteome: their thiolate side chain combines high nucleophilicity with redox sensitivity, making them prime targets for a diverse and ever-expanding array of post-translational modifications (PTMs).
Milos R. Filipovic
doaj   +1 more source

Protein persulfidation: A ubiquitous modification regulating a broad spectrum of biological processes

Hydrogen sulfide signaling occurs mainly through protein persulfidation, which is an important post-translational modification and a highly dynamic process in plants.
Gotor Martínez, Cecilia, Luque, Carmen, Carrillo, Reyes, Romero González, Luis Carlos, Montesinos-Pereira, David, Aroca, Angeles   +5 more
core   +1 more source

Endogenous hydrogen sulfide persulfidates endothelin type A receptor to inhibit pulmonary arterial smooth muscle cell proliferation

Redox Biology
Background: The binding of endothelin-1 (ET-1) to endothelin type A receptor (ETAR) performs a critical action in pulmonary arterial smooth muscle cell (PASMC) proliferation leading to pulmonary vascular structural remodeling.
Yanan Zhang, Xiaoyu Tian, Liangyi Chen, Shiqun Zhao, Xinjing Tang, Xin Liu, Dan Zhou, Chaoshu Tang, Bin Geng, Junbao Du, Hongfang Jin, Yaqian Huang   +11 more
doaj   +1 more source

Hydrogen sulfide signaling in plant response to temperature stress

Frontiers in Plant Science
For the past 300 years, hydrogen sulfide (H2S) has been considered a toxic gas. Nowadays, it has been found to be a novel signaling molecule in plants involved in the regulation of cellular metabolism, seed germination, plant growth, development, and ...
Zhong-Guang Li, Zhong-Guang Li, Zhong-Guang Li, Jue-Rui Fang, Jue-Rui Fang, Jue-Rui Fang, Su-Jie Bai, Su-Jie Bai, Su-Jie Bai   +8 more
doaj   +1 more source

Hydrogen sulfide protects against spinal cord pyroptosis via persulfidation of Rac1 after lumbosacral plexus nerve injury

Cell Death Discovery
Pyroptosis, a form of lytic and inflammatory programmed cell death mediated by gasdermin proteins, contributes to progressive spinal cord neurodegeneration following neural trauma.
Jianyu Mao, Jiajia Lu, Sheng Wang, Xin Jiang, Jing Li, Qiang Fu, Nan Lu, Lei Zhu, Aimin Chen, Jun Ma   +9 more
doaj   +1 more source

Synthesis, Characterization, and Reactivity of a Synthetic End-on Cobalt (II) Alkyl Persulfide Complex as a Model Platform for Thiolate Persulfidation

Journal of the American Chemical Society
Persulfides (RSS-) are ubiquitous source of sulfides (S2-) in biology, and interactions between RSS- and bioinorganic metal centers play critical roles in biological hydrogen sulfide (H2S) biogenesis, signaling, and catabolism. Here, we report the use of contact-ion stabilized [Na(15-crown-5)][tBuSS] (1) as a simple synthon to access rare metal alkyl ...
Keyan Li, Lev N. Zakharov, Michael D. Pluth   +2 more
openaire   +2 more sources

Hydrogen Sulfide-Induced Barley Resilience to Drought and Salinity through Protein Persulfidation

Chemicals and CAS Registry Numbers hydrogen sulfide 15035-72-0, 7783-06-4 sulfide 18496-25-8 Hydrogen Sulfide Plant Proteins Reactive Oxygen Species sodium bisulfide SulfidesBarley (Hordeum vulgare) is a widely cultivated cereal crops, and ...
Romero, Luis C., Moreno-González, María Inmaculada, Carrillo, Reyes, Aroca, Angeles, Gotor, Cecilia   +4 more
core   +1 more source

Persulfidation of plant and bacteroid proteins is involved in legume nodule development and senescence

17 Pags.- 8 Figs.- 2 Tabls. The data that support the findings of this study are available from the corresponding author upon reasonable request.
Tian, Tao, Becana Ausejo, Manuel, Romero, Luis C., Román Fernández, Ángela, Matamoros Galindo, Manuel Ángel   +4 more
core   +1 more source

Chemical tools: Pass the persulfides [PDF]

Nature Chemical Biology, 2014
openaire   +1 more source