Results 111 to 120 of about 444 (152)
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Molecular Plant, 2021
Post-translational modifications (PTMs), including phosphorylation and persulfidation, regulate the activity of SNF1-RELATED PROTEIN KINASE2.6 (SnRK2.6). Here, we report how persulfidations and phosphorylations of SnRK2.6 influence each other. The persulfidation of cysteine C131/C137 alters SnRK2.6 structure and brings the serine S175 residue closer to
Sisi Chen +2 more
exaly +3 more sources
Post-translational modifications (PTMs), including phosphorylation and persulfidation, regulate the activity of SNF1-RELATED PROTEIN KINASE2.6 (SnRK2.6). Here, we report how persulfidations and phosphorylations of SnRK2.6 influence each other. The persulfidation of cysteine C131/C137 alters SnRK2.6 structure and brings the serine S175 residue closer to
Sisi Chen +2 more
exaly +3 more sources
Thiiranes: Intelligent Molecules for S-Persulfidation
Journal of the American Chemical SocietyThis study presents a global strategy for the transsulfuration of intracellular thiols (RSH) to persulfides (RSSH). Thiiranes comprising fluorenyl/diphenyl and malonate ester moieties directly convert intercellular RSH to low-molecular-weight RSSH in cells.
Hoe-In Kim +6 more
openaire +3 more sources
Ergothioneine improves healthspan of aged animals by enhancing cGPDH activity through CSE-dependent persulfidation [PDF]
Cell MetabolismErgothioneine (ET), a dietary thione/thiol, is receiving growing attention for its possible benefits in healthy aging and metabolic resilience. Our study investigates ET’s effects on healthspan in aged animals, revealing lifespan extension and enhanced ...
Dunja Petrović +2 more
exaly +5 more sources
Hydrogen sulfide-linked persulfidation of ABI4 controls ABA responses through the transactivation of MAPKKK18 in Arabidopsis [PDF]
Molecular Plant, 2021 Hydrogen sulfide (H2S) is a signaling molecule that regulates plant hormone and stress responses. The phytohormone abscisic acid (ABA) plays an important role in plant adaptation to unfavorable environmental conditions and induces the persulfidation of L-
Jie Shen, Heng Zhou, Cecilia Gotor
exaly +2 more sources
Persulfidation protects from oxidative stress under nonphotorespiratory conditions in Arabidopsis
New Phytologist, 2023 Hydrogen sulfide is a signaling molecule in plants that regulates essential biological processes through protein persulfidation. However, little is known about sulfide-mediated regulation in relation to photorespiration.
Margarita García-Calderón +2 more
exaly +2 more sources
Methods in sulfide and persulfide research
Nitric Oxide, 2021Sulfides and persulfides/polysulfides (R-Sn-R', n > 2; R-Sn-H, n > 1) are endogenously produced metabolites that are abundant in mammalian and human cells and tissues. The most typical persulfides that are widely distributed among different organisms include various reactive persulfides-low-molecular-weight thiol compounds such as cysteine ...
Tsuyoshi Takata +9 more
openaire +2 more sources
ACS Chemical Biology, 2022
Persulfides (RSSH) are important reactive sulfur species (RSS) that are intertwined with the biological functions of hydrogen sulfide (H2S). The direct study of persulfides is difficult, however, due to their both nucleophilic and electrophilic character, which leads to the generation of an equilibrium of different RSS.
Kaylin G. Fosnacht +4 more
openaire +2 more sources
Persulfides (RSSH) are important reactive sulfur species (RSS) that are intertwined with the biological functions of hydrogen sulfide (H2S). The direct study of persulfides is difficult, however, due to their both nucleophilic and electrophilic character, which leads to the generation of an equilibrium of different RSS.
Kaylin G. Fosnacht +4 more
openaire +2 more sources
Current approaches for detection of hydrogen sulfide and persulfidation in biological systems
Plant Physiology and Biochemistry, 2020 The past decades have witnessed hydrogen sulfide (H2S) serving as gaseous signaling molecule participating in diverse cellular and physiological processes in biological systems.
Mingjian Zhou +2 more
exaly +2 more sources
Direct Zinc Finger Protein Persulfidation by H2S Is Facilitated by Zn2+
Angewandte Chemie - International Edition, 2019 H(2)S is a gaseous signaling molecule that modifies cysteine residues in proteins to form persulfides (P-SSH). One family of proteins modified by H(2)S are zinc finger (ZF) proteins, which contain multiple zinc coordinating cysteine residues.
Mike Lange, Kiwon Ok, Lajos Marko
exaly +2 more sources
Acidity and nucleophilic reactivity of persulfides
The FASEB Journal, 2022Persulfides(RSSH/RSS ‐ ) are chemical compounds related to thiols (RSH) and hydrogen sulfide (H 2 S). They participate in sulfur trafficking and processing, and are proposed to be transducers of the signaling effects of H 2
Dayana Benchoam +3 more
openaire +1 more source