Results 91 to 100 of about 3,419 (230)
, 2016 Describing the organization of substrates and substrate analogues in the active site of cysteine dioxygenase identifies potential intermediates in this critical yet poorly understood reaction, the oxidation of cysteine to cysteine sulfinic acid.
Egor P. Tchesnokov (1893004) +5 more
core +1 more source
, 2020 Related biologically to the known gasotransmitter hydrogen sulfide (H2S), persulfides (R–SSH) have recently been recognized as native signaling compounds and redox regulators in their own right.
John B. Matson (1443253) +9 more
core +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Spectral Signatures of Hydrogen Thioperoxide (HOSH) and Hydrogen Persulfide (HSSH): Possible Molecular Sulfur Sinks in the Dense ISM [PDF]
, 2022 C. Zachary Palmer +2 more
openalex +1 more source
Protein Science, Volume 35, Issue 1, January 2026.Abstract Repair of Iron Centers (RIC) proteins are present in several pathogens, including Staphylococcus aureus, contributing to resistance to nitroxidative stress and virulence. In this work, we investigated the molecular mechanisms by which S. aureus RIC facilitates iron mobilization, through structural analyses and functional studies.
Frederico M. Lourenço +8 more
wiley +1 more source
, 2019 Uranium is a risk-driving radionuclide in both radioactive waste disposal and contaminated land scenarios. In these environments, a range of biogeochemical processes can occur, including sulfate reduction, which can induce sulfidation of iron (oxyhydr ...
Naomi E. R. Ofili (8118254) +21 more
core +2 more sources
Aberrant Attachment of Heme to Cytochrome by the Ccm System Results in a Cysteine Persulfide Linkage
, 2016 Aberrant Attachment of Heme to Cytochrome by the Ccm System Results in a Cysteine Persulfide ...
Elizabeth B. Sawyer (224153) +4 more
core +1 more source
, 2020 Reactive sulfur species, such as hydrogen sulfide, persulfides, and polysulfides, have recently emerged as key signaling molecules and important physiological mediators within mammalian systems.
Madison, Kalk +5 more
core +1 more source
NRF2 signalling in cytoprotection and metabolism
British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami +4 more
wiley +1 more source
Persulfide Formation Mediates Cysteine and Homocysteine Biosynthesis in Methanosarcina acetivorans
, 2017 The mechanisms of sulfur uptake and trafficking in methanogens inhabiting sulfidic environments are highly distinctive. In aerobes, sulfur transfers between proteins occur via persulfide relay, but direct evidence for persulfides in methanogens has been ...
John Klimek (1849783) +3 more
core +1 more source