Results 111 to 120 of about 3,419 (230)

Persulfide Reactivity in the Detection of Protein S‑Sulfhydration

, 2016
Hydrogen sulfide (H2S) has emerged as a new member of the gaseous transmitter family of signaling molecules and appears to play a regulatory role in the cardiovascular and nervous systems.
Kate S. Carroll (516989), Jia Pan (1457566)   +1 more
core   +1 more source

The Role of Persulfide Metabolism During Arabidopsis Seed Development Under Light and Dark Conditions

Frontiers in Plant Science, 2018
The sulfur dioxygenase ETHE1 oxidizes persulfides in the mitochondrial matrix and is involved in the degradation of L-cysteine and hydrogen sulfide. ETHE1 has an essential but as yet undefined function in early embryo development of Arabidopsis thaliana.
Christin Lorenz, Saskia Brandt, Ljudmilla Borisjuk, Hardy Rolletschek, Nicolas Heinzel, Takayuki Tohge, Alisdair R. Fernie, Hans-Peter Braun, Tatjana M. Hildebrandt   +8 more
doaj   +1 more source

Mining proteomes for zinc finger persulfidation

RSC Chemical Biology
A meta-analysis of 22 persulfide-specific proteomics datasets reveals widespread persulfidation of zinc finger proteins across various species, highlighting the role of persulfidation as an important post-translational modification.
Haoju Li, Andrew T. Stoltzfus, Sarah L. J. Michel   +2 more
openaire   +2 more sources

Catalytic Mechanism of Sep-tRNA:Cys-tRNA Synthase SULFUR TRANSFER IS MEDIATED BY DISULFIDE AND PERSULFIDE

, 2012
Sep-tRNA: Cys-tRNA synthase (SepCysS) catalyzes the sulfhydrylation of tRNA-boundO-phosphoserine (Sep) to form cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) in methanogens that lack the canonical cysteinyl-tRNA synthetase (CysRS).
Dean, D., Dos Santos, P., Liu, Y., Orlando, R., Soell, D., Yuan, J. ; https://orcid.org/, Zhu, X.   +6 more
core   +1 more source

MarR family proteins sense sulfane sulfur in bacteria

mLife
Members of the multiple antibiotic resistance regulator (MarR) protein family are ubiquitous in bacteria and play critical roles in regulating cellular metabolism and antibiotic resistance.
Guanhua Xuan, Luying Xun, Yongzhen Xia
doaj   +1 more source

Cysteine Persulfide Formation by Enterobacteriaceae Bacteria and Cloned Mammalian Cystathionine γ-Lyase

, 2021
Polysulfides and persulfides (RSSxR and RSSH) have become topics of significant interest due to prevalence in eukaryotic and prokaryotic systems. Cysteine trisulfide (CysSSSCys) has been found to be able to be reduced by Escherichia coli and produce ...
Irwin, Drew
core  

The structure of the SufS–SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis

Fe-S clusters are critical cofactors for redox chemistry in all organisms. The cysteine desulfurase, SufS, provides sulfur in the SUF Fe-S cluster bioassembly pathway.
Frantom, Patrick A., Dunkle, Jack A., Chhikara, Nidhi, Vo, Minh, Gilbert, Nathaniel C., Gogar, Rajleen K.   +5 more
core   +1 more source

Versatile roles of cysteine persulfides in tumor biology

Current Opinion in Chemical Biology
Rewiring the transsulfuration pathway is recognized as a rapid adaptive metabolic response to environmental conditions in cancer cells to support their increased cysteine demand and to produce Reactive Sulfur Species (RSS) including hydrogen sulfide (H2S) and cysteine persulfide.
Klaudia Borbényi-Galambos, Ágnes Czikora, Katalin Erdélyi, Péter Nagy   +3 more
openaire   +2 more sources

Polysulfide and persulfide-mediated activation of the PERK-eIF2α-ATF4 pathway increases Sestrin2 expression and reduces methylglyoxal toxicity

Redox Biology
Unfolded protein response (UPR) is activated in cells under endoplasmic reticulum (ER) stress. One sensor protein involved in this response is PERK, which is activated through its redox-dependent oligomerization.
Shin Koike, Hideo Kimura, Yuki Ogasawara
doaj   +1 more source

Thioglucose-derived tetrasulfide, a unique polysulfide model compound

Redox Biology
Polysulfides have received increased interest in redox biology due to their role as the precursors of H2S and persulfides. However, the compounds that are suitable for biological investigations are limited to cysteine- and glutathione-derived ...
Stephen Lindahl, Meg Shieh, Tianli Zhang, Chunyu Guo, Jerome R. Robinson, Tomohiro Sawa, Ming Xian   +6 more
doaj   +1 more source