Results 121 to 130 of about 3,419 (230)

Quantitative persulfide site identification (qPerS-SID) reveals protein targets of H₂S releasing donors in mammalian cells

, 2016
H2S is an important signalling molecule involved in diverse biological processes. It mediates the formation of cysteine persulfides (R-S-SH), which affect the activity of target proteins. Like thiols, persulfides show reactivity towards electrophiles and
Wittig, Ilka, Longen, Sebastian, Köhler, Yvette, Richter, Florian, Pfeilschifter, Josef, Beck, Karl-Friedrich   +5 more
core   +1 more source

Solution Structures and Backbone Dynamics of Escherichia coli Rhodanese PspE in Its Sulfur-Free and Persulfide-Intermediate Forms: Implications for the Catalytic Mechanism of Rhodanese^,

, 2016
Rhodanese catalyzes the sulfur-transfer reaction that transfers sulfur from thiosulfate to cyanide by a double-displacement mechanism, in which an active cysteine residue plays a central role.
Xue Kang (2443252), Changwen Jin (260274), Fan Yang (1413), Bin Xia (162982), Hongwei Li (17402)   +4 more
core   +1 more source

Longevity control by supersulfide-mediated mitochondrial respiration and regulation of protein quality

Redox Biology
Supersulfides, which are defined as sulfur species with catenated sulfur atoms, are increasingly being investigated in biology. We recently identified pyridoxal phosphate (PLP)-dependent biosynthesis of cysteine persulfide (CysSSH) and related ...
Akira Nishimura, Sunghyeon Yoon, Tetsuro Matsunaga, Tomoaki Ida, Minkyung Jung, Seiryo Ogata, Masanobu Morita, Jun Yoshitake, Yuka Unno, Uladzimir Barayeu, Tsuyoshi Takata, Hiroshi Takagi, Hozumi Motohashi, Albert van der Vliet, Takaaki Akaike   +14 more
doaj   +1 more source

Proton and Lithium cation interactions with hydrogen sulfide and hydrogen persulfide

, 1989
The interaction of hydrogen sulfide and hydrogen persulfide with protons and lithium cations was examined by means of ab initio 6–31G* calculations. The influence of the correlation energy for selected complexes was estimated. Contrary to former results,
R. Cammi, CIMIRAGLIA, Renzo, J. Tomasi, H. Hofmann   +3 more
core   +1 more source

Abstracts

Cancer Science, Volume 117, Issue S1, Page 1-2148, January 2026.
wiley   +1 more source

A Vinyl-Boronate Ester-Based Persulfide Donor Controllable by Hydrogen Peroxide, a Reactive Oxygen Species (ROS)

, 2018
A vinyl boronate ester-based persulfidating agent that is selectively activated by hydrogen peroxide, which is a reactive oxygen species (ROS), and efficiently generated a persulfide by a hitherto unexplored 1,4-O,S-relay mechanism is reported.
Harinath Chakrapani (1743040), Suman Manna (5172203), Preeti Chauhan (3593774), Prerona Bora (3593768)   +3 more
core   +1 more source

Hydropersulfides promote angiogenesis and preserve vascular function

Redox Biology
Hydropersulfides (RSSH) are increasingly recognized as key mediators in redox signalling in mammalian cells, although their physiological functions, especially in angiogenesis, remain unknown. Direct mechanistic investigation of RSSH has been challenging
Reece J. Lamb, Fifi S. Ibrahim, Vinayak S. Khodade, Scott P. Davies, Kayleigh Griffiths, Tsuyoshi Takata, Jinjing Gu, Tetsuro Matsunaga, Roger J. Grand, Francesca M. Nichols, Alice J. Barton, Aisah A. Aubdool, Masanobu Morita, Hozumi Motohashi, Ming Xian, Takaaki Akaike, John P. Toscano, Melanie Madhani   +17 more
doaj   +1 more source

Hypothesis Paper How Super is Supersulfide?: Reconsidering Persulfide Reactivity in Cellular Biology

, 2023
Christopher Switzer
openalex   +1 more source

Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols

Friedreich's ataxia is a severe neurodegenerative disease caused by the decreased expression of frataxin, a mitochondrial protein that stimulates iron sulfur (Fe-S) cluster biogenesis.
Grandas Sagarra, Anna, D'Autréaux, Benoit, Cornu, David, Elduque Busquets, Xavier, Le Caer, Jean-Pierre, Belot, Laura, Parent, Aubérie, Toledano, Michel B.   +7 more
core  

Crystal structure of human persulfide dioxygenase: structural basis of ethylmalonic encephalopathy [PDF]

, 2015
I. Pettinati, Jürgen Brem, M.A. McDonough, Christopher J. Schofield   +3 more
openalex   +1 more source