Results 71 to 80 of about 3,419 (230)
One- and Two-Photon-Activated Cysteine Persulfide Donors for Biological Targeting
, 2019 Persulfides have been considered as potential signaling compounds similar to the H2S in “S-persulfidation”, a sulfur-mediated redox cycle. The research of this sulfur-mediated species is hindered because of the lack of efficient persulfide donors.
N. D. Pradeep Singh (7337156) +5 more
core +1 more source
Advanced Science, Volume 13, Issue 31, 4 June 2026.We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source
Transpersulfidation or H2S Release? Understanding the Landscape of Persulfide Chemical Biology
Persulfides (RSSH) are biologically important reactive sulfur species that are endogenously produced, protect key cysteine residues from irreversible oxidation, and are important intermediates during different enzymatic processes.
Pier Alexandre, Champagne +3 more
core +2 more sources
Aging Cell, Volume 25, Issue 5, May 2026.Cellular senescence and mitochondrial dysfunction disrupt adipose tissue homeostasis during aging, but mechanisms remain unclear. HDAC9 expression increases with age in mouse adipose tissue and Hdac9 knockout mice showed reduced fat mass, senescence markers, and enhanced mitochondrial gene expression, respiration, and thiosulfate sulfurtransferase (Tst)
Brandee Goo +15 more
wiley +1 more source
, 2014 International audienceFriedreich's ataxia is a severe neurodegenerative disease caused by the decreased expression of frataxin, a mitochondrial protein that stimulates iron-sulfur (Fe-S) cluster biogenesis.
d'Autréaux, Benoit +7 more
core +2 more sources
Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond
Advanced Science, Volume 13, Issue 23, 23 April 2026.Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi +4 more
wiley +1 more source
Increased intracellular H2S levels enhance iron uptake in Escherichia coli
mBioWe investigated the impact of intracellular hydrogen sulfide (H2S) hyperaccumulation on the transcriptome of Escherichia coli. The wild-type (WT) strain overexpressing mstA, encoding 3-mercaptopyruvate sulfur transferase, produced significantly higher ...
Shouta Nonoyama +6 more
doaj +1 more source
The FASEB Journal, Volume 40, Issue 6, 31 March 2026.A subpopulation of MDCK (NBL‐2) cells, an epithelial cell line derived from the normal kidney, expresses DAO and 3MST. The DAO/3MST‐expressing cells are progressively eliminated during passaging; however, clonal isolation enables the establishment of sublines that maintain stable H2S production. Clonal cells co‐expressing DAO and 3MST therefore provide
Akari Miyamoto +4 more
wiley +1 more source
Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology
Molecules, 2014 The understanding of sulfur bonding is undergoing change. Old theories on hypervalency of sulfur and the nature of the chalcogen-chalcogen bond are now questioned.
John I. Toohey, Arthur J. L. Cooper
doaj +1 more source
Persulfide Formation Mediates Cysteine and Homocysteine Biosynthesis in Methanosarcina acetivorans
, 2017 The mechanisms of sulfur uptake and trafficking in methanogens inhabiting sulfidic environments are highly distinctive. In aerobes, sulfur transfers between proteins occur via persulfide relay, but direct evidence for persulfides in methanogens has been ...
John J. Perona +7 more
core +1 more source