Results 61 to 70 of about 3,419 (230)

The ABCB7-Like Transporter PexA in Rhodobacter capsulatus Is Involved in the Translocation of Reactive Sulfur Species

Frontiers in Microbiology, 2019
The mitochondrial ATP-binding cassette (ABC) transporters ABCB7 in humans, Atm1 in yeast and ATM3 in plants, are highly conserved in their overall architecture and particularly in their glutathione binding pocket located within the transmembrane spanning
Simona Riedel, Beata Siemiatkowska, Mutsumi Watanabe, Christina S. Müller, Volker Schünemann, Rainer Hoefgen, Silke Leimkühler   +6 more
doaj   +1 more source

The Multifaceted Bacterial Cysteine Desulfurases: From Metabolism to Pathogenesis

Antioxidants, 2021
Living cells have developed a relay system to efficiently transfer sulfur (S) from cysteine to various thio-cofactors (iron-sulfur (Fe-S) clusters, thiamine, molybdopterin, lipoic acid, and biotin) and thiolated tRNA. The presence of such a transit route
Mayashree Das, Arshiya Dewan, Somnath Shee, Amit Singh   +3 more
doaj   +1 more source

Shared Sulfur Mobilization Routes for tRNA Thiolation and Molybdenum Cofactor Biosynthesis in Prokaryotes and Eukaryotes

Biomolecules, 2017
Modifications of transfer RNA (tRNA) have been shown to play critical roles in the biogenesis, metabolism, structural stability and function of RNA molecules, and the specific modifications of nucleobases with sulfur atoms in tRNA are present in pro- and
Silke Leimkühler, Martin Bühning, Lena Beilschmidt   +2 more
doaj   +1 more source

Cupriavidus pinatubonensis JMP134 Alleviates Sulfane Sulfur Toxicity after the Loss of Sulfane Dehydrogenase through Oxidation by Persulfide Dioxygenase and Hydrogen Sulfide Release

Metabolites, 2023
An incomplete Sox system lacking sulfane dehydrogenase SoxCD may produce and accumulate sulfane sulfur when oxidizing thiosulfate. However, how bacteria alleviate the pressure of sulfane sulfur accumulation remains largely unclear.
Yufeng Xin, Yaxin Wang, Honglin Zhang, Yu Wu, Yongzhen Xia, Huanjie Li, Xiaohua Qu   +6 more
doaj   +1 more source

Synthesis of a Uranyl Persulfide Complex and Quantum Chemical Studies of Formation and Topologies of Hypothetical Uranyl Persulfide Cage Clusters

, 2016
The compound Na4[(UO2)­(S2)3]­(CH3OH)8 was synthesized at room temperature in an oxygen-free environment. It contains a rare example of the [(UO2)­(S2)3]4– complex in which a uranyl ion is coordinated by three bidentate persulfide groups.
Laura Gagliardi (1279068), Daniel J. Grant (1673167), Zhehui Weng (1705096), Peter C. Burns (1438396), Laurent J. Jouffret (1851799)   +4 more
core   +2 more sources

Thiosulfonate‐Derived BODIPY “Stick and Glue” Strategy for Fluorescent Thiol Labeling

Angewandte Chemie, Volume 138, Issue 6, 2 February 2026.
We present a powerful photochemical strategy for converting disulfide bonds into stable thioether linkages via a [1,2]‐sigmatropic rearrangement. By integrating this reaction into traditional methanethiosulfonate‐based thiol labeling, we enable light‐triggered stabilization of peptide and protein conjugates with enhanced robustness and versatility ...
Lucie Šálková, David Dunlop, B. Buse Tütüncü, Zdeněk Knejzlík, Tomáš Slanina   +4 more
wiley   +2 more sources

Sulfide Homeostasis and Nitroxyl Intersect via Formation of Reactive Sulfur Species in Staphylococcus aureus

mSphere, 2017
Staphylococcus aureus is a commensal human pathogen and a major cause of nosocomial infections. As gaseous signaling molecules, endogenous hydrogen sulfide (H2S) and nitric oxide (NO·) protect S.
Hui Peng, Jiangchuan Shen, Katherine A. Edmonds, Justin L. Luebke, Anne K. Hickey, Lauren D. Palmer, Feng-Ming James Chang, Kevin A. Bruce, Thomas E. Kehl-Fie, Eric P. Skaar, David P. Giedroc   +10 more
doaj   +1 more source

Rhodaneses minimize the accumulation of cellular sulfane sulfur to avoid disulfide stress during sulfide oxidation in bacteria

Redox Biology, 2022
Heterotrophic bacteria and human mitochondria often use sulfide: quinone oxidoreductase (SQR) and persulfide dioxygenase (PDO) to oxidize sulfide to sulfite and thiosulfate.
Mingxue Ran, Qingbin Li, Yufeng Xin, Shaohua Ma, Rui Zhao, Min Wang, Luying Xun, Yongzhen Xia   +7 more
doaj   +1 more source

Sulfur metabolic response in macrophage limits excessive inflammatory response by creating a negative feedback loop

Redox Biology, 2023
The excessive inflammatory response of macrophages plays a vital role in the pathogenesis of various diseases. The dynamic metabolic alterations in macrophages, including amino acid metabolism, are known to orchestrate their inflammatory phenotype.
Haruna Takeda, Shohei Murakami, Zun Liu, Tomohiro Sawa, Masatomo Takahashi, Yoshihiro Izumi, Takeshi Bamba, Hideyo Sato, Takaaki Akaike, Hiroki Sekine, Hozumi Motohashi   +10 more
doaj   +1 more source

How super is supersulfide?: Reconsidering persulfide reactivity in cellular biology

Redox Biology, 2023
In an attempt to understand the cellular mechanisms of H2S signalling, recent research has focused on supersulfide (i.e., alkyl and inorganic hydropersulfide) formation and subsequent reactivity.
Christopher H. Switzer
doaj   +1 more source