Results 71 to 80 of about 4,338 (207)

Increased intracellular H2S levels enhance iron uptake in Escherichia coli

mBio
We investigated the impact of intracellular hydrogen sulfide (H2S) hyperaccumulation on the transcriptome of Escherichia coli. The wild-type (WT) strain overexpressing mstA, encoding 3-mercaptopyruvate sulfur transferase, produced significantly higher ...
Shouta Nonoyama, Shintaro Maeno, Yasuhiro Gotoh, Ryota Sugimoto, Kan Tanaka, Tetsuya Hayashi, Shinji Masuda   +6 more
doaj   +1 more source

Thiosulfoxide (Sulfane) Sulfur: New Chemistry and New Regulatory Roles in Biology

Molecules, 2014
The understanding of sulfur bonding is undergoing change. Old theories on hypervalency of sulfur and the nature of the chalcogen-chalcogen bond are now questioned.
John I. Toohey, Arthur J. L. Cooper
doaj   +1 more source

Iron‐Based Materials for Advanced Lithium/Sodium‐Ion Batteries

ChemSusChem, Volume 19, Issue 4, 25 February 2026.
This Review examines iron‐based anode materials for lithium‐ and sodium‐ion batteries, emphasizing how phase chemistry (sulfides, oxides, and metal–organic framework (MOF)‐derived compounds), multiscale structural engineering, and interface regulation collectively address volume expansion, conductivity limitations, and cycling instability, while ...
Jianfeng Hou, Xihan Tan, Honglei Zhang, Ning Han, Lei Jiang, Dechao Chen   +5 more
wiley   +1 more source

Mechanism and structural dynamics of sulfur transfer during de novo [2Fe-2S] cluster assembly on ISCU2

Nature Communications
Maturation of iron-sulfur proteins in eukaryotes is initiated in mitochondria by the core iron-sulfur cluster assembly (ISC) complex, consisting of the cysteine desulfurase sub-complex NFS1-ISD11-ACP1, the scaffold protein ISCU2, the electron donor ...
Vinzent Schulz, Ralf Steinhilper, Jonathan Oltmanns, Sven-A. Freibert, Nils Krapoth, Uwe Linne, Sonja Welsch, Maren H. Hoock, Volker Schünemann, Bonnie J. Murphy, Roland Lill   +10 more
doaj   +1 more source

Rapid and selective generation of H2S within mitochondria protects against cardiac ischemia-reperfusion injury

Redox Biology, 2022
Mitochondria-targeted H2S donors are thought to protect against acute ischemia-reperfusion (IR) injury by releasing H2S that decreases oxidative damage.
Jan Lj. Miljkovic, Nils Burger, Justyna M. Gawel, John F. Mulvey, Abigail A.I. Norman, Takanori Nishimura, Yoshiyuki Tsujihata, Angela Logan, Olga Sauchanka, Stuart T. Caldwell, Jordan L. Morris, Tracy A. Prime, Stefan Warrington, Julien Prudent, Georgina R. Bates, Dunja Aksentijević, Hiran A. Prag, Andrew M. James, Thomas Krieg, Richard C. Hartley, Michael P. Murphy   +20 more
doaj   +1 more source

Gut microbiota facilitates dietary heme-induced epithelial hyperproliferation by opening the mucus barrier in colon [PDF]

, 2015
Colorectal cancer risk is associated with diets high in red meat. Heme, the pigment of red meat, induces cytotoxicity of colonic contents and elicits epithelial damage and compensatory hyperproliferation, leading to hyperplasia.
Clara Belzer, Giovannucci, Guido J. Hooiveld, Jan Dekker, Lapré, McGarr, Michael Müller, Michiel Kleerebezem, Noortje Ijssennagger, Roelof van der Meer, Saskia W. C. van Mil, Sesink, Sheffner, van Klinken   +13 more
core   +2 more sources

Formation of persulfide groups in alkaline treated insulin [PDF]

FEBS Letters, 1970
Alkaline treatment of disulfidecontaining proteins is known to produce a number of unusual compounds related with the degradation of the cystinyl residues. Lanthionine [l] and lysinoalanine [2] are among the products identified with certainly, while dehydroala- nine [2] , thiocysteine [3,4] , cysteine sulfenic acid [S] and other products are supposed ...
Cavallini, D., Federici, G., Barboni, E., Marcucci, M.   +3 more
openaire   +2 more sources

Continued surprises in the cytochrome c biogenesis story. [PDF]

, 2012
Cytochromes c covalently bind their heme prosthetic groups through thioether bonds between the vinyl groups of the heme and the thiols of a CXXCH motif within the protein.
Barker, Paul D, Sawyer, Elizabeth B
core   +1 more source

Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin, Chen Qian, Wenhao Li, Qihan Wang, Qifeng Sheng, Zheqing Chen, Wei Zhang, Wenming Li, Gaoran Ge, Zhanjun Yan, Dechun Geng   +10 more
wiley   +1 more source

Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation

Redox Biology, 2017
Many physiological functions of hydrogen sulfide (H2S) have been reported in mammalian cells over the last 20 years. These physiological effects have been ascertained through in vitro treatment of cells with Na2S or NaHS, both of which are precursors of ...
Shin Koike, Shoichi Nishimoto, Yuki Ogasawara   +2 more
doaj   +1 more source