Results 81 to 90 of about 1,224 (162)

Versatile roles of cysteine persulfides in tumor biology

Current Opinion in Chemical Biology
Rewiring the transsulfuration pathway is recognized as a rapid adaptive metabolic response to environmental conditions in cancer cells to support their increased cysteine demand and to produce Reactive Sulfur Species (RSS) including hydrogen sulfide (H2S) and cysteine persulfide.
Klaudia Borbényi-Galambos, Ágnes Czikora, Katalin Erdélyi, Péter Nagy   +3 more
openaire   +2 more sources

The Role of Hydrogen Sulfide in the Regulation of the Pulmonary Vasculature in Health and Disease

Antioxidants
The gasotransmitter hydrogen sulfide (H2S; also termed sulfide) generally acts as a vasodilator in the systemic vasculature but causes a paradoxical constriction of pulmonary arteries (PAs).
Philip I. Aaronson
doaj   +1 more source

Unique response of polysulfide in serum albumin to oxidative stress

Scientific Reports
Supersulfide species have been identified as molecules that have catenated sulfur atoms as persulfides (R-SSH) and polysulfides (R-SSnH). The physiological activities of intracellular supersulfides have been widely studied, but little is known about the ...
Mayumi Ikeda-Imafuku, Maki Sakai, Keitaro Umezawa, Hidehiko Nakagawa, Toru Maruyama, Masaki Otagiri, Takaaki Akaike, Tomohiro Sawa, Ming Xian, Yuri Miura, Tatsuhiro Ishida, Yu Ishima   +11 more
doaj   +1 more source

Thiosulphate sulfurtransferase: Biological roles and therapeutic potential

Redox Biology
Mitochondria are central to eukaryotic cell function, driving energy production, intermediary metabolism, and cellular homeostasis. Dysregulation of mitochondrial function often results in oxidative stress, a hallmark of numerous diseases, underscoring ...
Yang Luo, Shaden Melhem, Martin Feelisch, Laurent Chatre, Nicholas M. Morton, Amalia M. Dolga, Harry van Goor   +6 more
doaj   +1 more source

The first and second zinc finger domains from Poly-ADP-ribose polymerase 1 (PARP1) are modified by hydrogen sulfide. [PDF]

J Biol Inorg Chem
Williams AJ, Michel SLJ.
europepmc   +1 more source

H₂S-mediated protein S-sulfhydration: a novel regulatory module in lipid metabolism. [PDF]

Front Cell Dev Biol
Pang M, Chen H, Li S, Yang H, Mao Y, Huang Y.   +5 more
europepmc   +1 more source

H₂S-Mediated Persulfidation of the Classical Zinc Finger Protein Yin-Yang 1. [PDF]

Biochemistry
Worth MM, Badeau LJ, Reitz AD, Michel SLJ.   +3 more
europepmc   +1 more source

Profiling the landscape of cysteine posttranslational modifications in brain aging and neurodegeneration. [PDF]

Neurotherapeutics
Filipovic MR.
europepmc   +1 more source

Role of Sulfide Quinone Oxidoreductase and Supersulfides in Hepatic Ischemia-Reperfusion Injury in Mice. [PDF]

Antioxidants (Basel)
Takamori S, Shirozu K, Marutani E, Takata T, Mizuta Y, Kawano T, Murata M, Ida T, Matsunaga T, Akaike T, Yamaura K, Akahoshi T.   +11 more
europepmc   +1 more source

Persulfidation of the zinc finger protein ZRANB2 modulates its RNA binding and alternative splicing function. [PDF]

J Inorg Biochem
Hursey MS, Reitz AD, Fidler SE, Michel SLJ.   +3 more
europepmc   +1 more source