Results 61 to 70 of about 14,681 (257)

Application of WeChat public platform in standardized training of surgical residents [PDF]

open access: yesJichu yixue yu linchuang, 2020
As a popular media sharing platform in recent years, WeChat public platform has great potential in education. This paper takes the public number “PUMC training and teaching” as an example to explore the application of WeChat public platform in ...
XIAO Jian-chun, ZHANG Miao-yan, XU Yuan, WU Bin
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Nighttime Pedestrian Ranging Algorithm Based on Monocular Vision

open access: yesCybernetics and Information Technologies, 2016
Since the traditional computer vision ranging algorithm is imperfect in pertinence and precision, night time monocular vision pedestrian ranging method is proposed for vehicular infrared night vision goggles.
Wang Hongxia, Kang Xue-Xue, Yu Yang
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Qualifying Causes as Pertinent.

open access: yes, 2018
Several computational methods have been proposed to evaluate the relevance of an instantiated cause to an observed consequence. The paper reports on an experiment to investigate the adequacy of some of these methods as descriptors of human judgments about causal relevance.
Sileno, Giovanni, Dessalles, Jean-Louis
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Foundations of Immunology and Their Pertinence to Medicine

open access: yesCentral Asian Journal of Medical Sciences, 2018
No abstract in ...
Mandakhnaran Davaadorj
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Universidade e pertinência social: alguns apontamentos para reflexão

open access: yesAvaliação: Revista da Avaliação da Educação Superior
Resumo: O presente artigo parte da ideia de que as universidades públicas brasileiras vêm passando por transformações significativas ao longo das últimas décadas.
Ana Carolina Spatti   +2 more
doaj   +1 more source

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