Results 81 to 90 of about 64,492 (258)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Pertinence of Incontinence

open access: yesPrincipia: An International Journal of Epistemology, 2005
In this paper I suggest a reconstruction of the traditional concepts of con-tinent and incontinent action. This reconstruction proceeds along the lines of a standpoint of bounded rationality.
António Zilhão
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Syntaxe logique et sémantique : leur pertinence linguistique

open access: yes, 1966
Chomsky Noam. Syntaxe logique et sémantique : leur pertinence linguistique. In: Langages, 1ᵉ année, n°2, 1966. Logique et linguistique, sous la direction de Ernest Coumet, Oswald Ducrot et Jean Gattégno. pp.
Chomsky, Noam
core   +1 more source

Médecine médiévale et plurilinguisme : de la pertinence des facteurs génériques

open access: yes, 2014
Médecine médiévale et plurilinguisme : de la pertinence des facteurs ...
Vedrenne-Fajolles, Isabelle
core   +2 more sources

Modeling the Transition of Private Pertinence into Collective Relevance in Internet Communication [PDF]

open access: yesАктуальные проблемы филологии и педагогической лингвистики
The following study describes the core modeling principles of correspondence of private pertinence to collective relevance, analyzes the mechanisms for creating generalized content, and the formation of common significance areas in the value space of ...
Sergey N. Bredikhin   +2 more
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Tartarin chez les Anglos : intraduisibilité et pertinence [PDF]

open access: yes, 1995
Tartarin chez les Anglos : intraduisibilité et pertinence – Cet article applique les concepts de la théorie de la pertinence de Sperber et Wilson à la comparaison de cinq traductions anglaises et américaines de Tartarin de Tarascon d'Alphonse Daudet ...
Romney, Claude
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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