Results 111 to 120 of about 51,446 (212)

Distinct phosphorylation clusters determines the signalling outcome of the free fatty acid receptor FFA4/GPR120 [PDF]

open access: yes, 2016
It is established that long-chain free fatty acids including ω-3 fatty acids mediate an array of biological responses through members of the free fatty acid receptor family, which includes FFA4.
Alvarez-Curto, Elisa   +7 more
core   +2 more sources

Molecular aspects of Bordetella pertussis pathogenesis [PDF]

open access: yes, 2010
The molecular mechanisms of Bordetella virulence are now well understood, and many virulence factors have been identified and characterized at the molecular level.
Camille Locht
core   +2 more sources

Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunity.

open access: yesPLoS ONE, 2011
Pertussis (whooping cough) is frequently complicated by concomitant infections with respiratory viruses. Here we report the effect of Bordetella pertussis infection on subsequent influenza virus (PR8) infection in mouse models and the role of pertussis ...
Victor I Ayala   +4 more
doaj   +1 more source

Construction of Minitransposons for Constitutive and Inducible Expression of Pertussis Toxin in Bvg-Negative Bordetella-Bronchiseptica [PDF]

open access: yes, 1991
Appropriately detoxified pertussis toxin (PT) of Bordetella pertussis is considered to be an essential component of new-generation whooping cough vaccines, but the development of a procedure to obtain high levels of purified toxin has been and continues ...
Rohde, Manfred   +3 more
core  

Activation of phospholipase C beta 2 by the alpha and beta gamma subunits of trimeric GTP-binding protein [PDF]

open access: yes, 1993
Cotransfection assays were used to show that the members of the GTP-binding protein Gq class of alpha subunits could activate phospholipase C (PLC) beta 2.
Katz, Arieh   +2 more
core  

Prevention of pertussis: An unresolved problem

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined.
Susanna Esposito, Nicola Principi
doaj   +1 more source

Seroprevalence of IgA and IgM antibodies to Bordetella pertussis in healthy Japanese donors: Assessment for the serological diagnosis of pertussis.

open access: yesPLoS ONE, 2019
Pertussis is a human respiratory infection caused by the gram-negative bacterium, Bordetella pertussis. To evaluate the pertussis burden and vaccine efficacy, diagnosis and epidemiological surveillance should be based on accurate and valid diagnostic ...
Rei Fumimoto   +6 more
doaj   +1 more source

Comparison of nasopharyngeal culture, polymerase chain reaction (PCR) and serological test for diagnosis of pertussis

open access: yesThe Turkish Journal of Pediatrics, 2009
This prospective study, which was designed to compare nasopharyngeal culture, polymerase chain reaction (PCR) and serology in the diagnosis of pertussis, covered 35 children aged between 0 and 16 who were admitted to Hacettepe University Ihsan ...
Ali Bülent Cengiz   +5 more
doaj  

Antibody avidity to pertussis toxin after acellular pertussis vaccination and infection. [PDF]

open access: yesEmerg Microbes Infect, 2023
Knuutila A   +7 more
europepmc   +1 more source

Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]

open access: yes, 2009
Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós   +2 more
core  

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