Results 101 to 110 of about 33,335 (199)
Inhibition of bombesin-induced mitogenesis by pertussis toxin : Dissociation from phospholipase C pathway [PDF]
Prior incubation of quiescent cultures of Swiss 3T3 cells with pertussis toxin selectively inhibited the stimulation of DNA synthesis induced by peptides of the bombesin family. While pertussis toxin blocked mitogenesis at an early stage in the action of
Nånberg, Eewa, +4 more
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Monocytes arriving at the site of infection differentiate into functional effector macrophages to replenish the resident sentinel cells. Bordetella pertussis, the pertussis agent, secretes an adenylate cyclase toxin-hemolysin (CyaA) that binds myeloid ...
Jawid Nazir Ahmad +6 more
doaj +1 more source
Pertussis (whooping cough) is frequently complicated by concomitant infections with respiratory viruses. Here we report the effect of Bordetella pertussis infection on subsequent influenza virus (PR8) infection in mouse models and the role of pertussis ...
Victor I Ayala +4 more
doaj +1 more source
Effect of pertussis toxin on α2-adrenoceptors: decreased formation of the high-affinity state for agonists [PDF]
Administration of pertussis toxin to hamsters abolishes the α2-adrenergic inhibition of adenylate cyclase in their adipocytes. The toxin did not modify the number of adipocyte α2-adrenoceptors or their affinity for antagonists.
Robert J. Lefkowitz +13 more
core +1 more source
Inhibition of endothelin-mediated topoisomerase I activation by pertussis toxin [PDF]
Cultured rat mesangial cells contain high affinity endothelin (ET) receptors at high densities. Exposure of these cells to ET resulted in a transient activation of topoisomerase I extractable activity, which reached its maximum value at approximately 2 ...
Michael R. Mattern +7 more
core +1 more source
Mishulow, Mowry and Scott1 demonstrated that exotoxic filtrates could be obtained from whooping cough cultures. They planted their organisms on chocolate agar over which they had poured a small amount of horse serum-beef heart broth. The small amount of diluent made the harvest of toxin necessarily small. On the other hand, Craster and Smith2 mentioned
J. A. Toomey, J. E. McClelland
openaire +1 more source
Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids [PDF]
The hydrophobic surfaces presumably involved in the membrane interaction of pertussis toxin have been mapped by a new detergent-binding assay. This is based on the interdispersion among detergent micelles of trace amounts of radioactive photoreactive ...
Montecucco, Cesare +7 more
core +1 more source
Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons [PDF]
: This study was designed to examine the ability of pertussis toxin to block various responses due to (-)-baclofen in cultured cerebellar granule neurons of the rat.
core
Prevention of pertussis: An unresolved problem
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined.
Susanna Esposito, Nicola Principi
doaj +1 more source
This prospective study, which was designed to compare nasopharyngeal culture, polymerase chain reaction (PCR) and serology in the diagnosis of pertussis, covered 35 children aged between 0 and 16 who were admitted to Hacettepe University Ihsan ...
Ali Bülent Cengiz +5 more
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