Results 101 to 110 of about 33,335 (199)

Inhibition of bombesin-induced mitogenesis by pertussis toxin : Dissociation from phospholipase C pathway [PDF]

open access: yes, 1987
Prior incubation of quiescent cultures of Swiss 3T3 cells with pertussis toxin selectively inhibited the stimulation of DNA synthesis induced by peptides of the bombesin family. While pertussis toxin blocked mitogenesis at an early stage in the action of
Nånberg, Eewa,   +4 more
core   +1 more source

Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells

open access: yesmBio, 2019
Monocytes arriving at the site of infection differentiate into functional effector macrophages to replenish the resident sentinel cells. Bordetella pertussis, the pertussis agent, secretes an adenylate cyclase toxin-hemolysin (CyaA) that binds myeloid ...
Jawid Nazir Ahmad   +6 more
doaj   +1 more source

Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunity.

open access: yesPLoS ONE, 2011
Pertussis (whooping cough) is frequently complicated by concomitant infections with respiratory viruses. Here we report the effect of Bordetella pertussis infection on subsequent influenza virus (PR8) infection in mouse models and the role of pertussis ...
Victor I Ayala   +4 more
doaj   +1 more source

Effect of pertussis toxin on α2-adrenoceptors: decreased formation of the high-affinity state for agonists [PDF]

open access: yes, 1984
Administration of pertussis toxin to hamsters abolishes the α2-adrenergic inhibition of adenylate cyclase in their adipocytes. The toxin did not modify the number of adipocyte α2-adrenoceptors or their affinity for antagonists.
Robert J. Lefkowitz   +13 more
core   +1 more source

Inhibition of endothelin-mediated topoisomerase I activation by pertussis toxin [PDF]

open access: yes, 1990
Cultured rat mesangial cells contain high affinity endothelin (ET) receptors at high densities. Exposure of these cells to ET resulted in a transient activation of topoisomerase I extractable activity, which reached its maximum value at approximately 2 ...
Michael R. Mattern   +7 more
core   +1 more source

Pertussis Toxin or Antigen

open access: yesExperimental Biology and Medicine, 1933
Mishulow, Mowry and Scott1 demonstrated that exotoxic filtrates could be obtained from whooping cough cultures. They planted their organisms on chocolate agar over which they had poured a small amount of horse serum-beef heart broth. The small amount of diluent made the harvest of toxin necessarily small. On the other hand, Craster and Smith2 mentioned
J. A. Toomey, J. E. McClelland
openaire   +1 more source

Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids [PDF]

open access: yes, 1986
The hydrophobic surfaces presumably involved in the membrane interaction of pertussis toxin have been mapped by a new detergent-binding assay. This is based on the interdispersion among detergent micelles of trace amounts of radioactive photoreactive ...
Montecucco, Cesare   +7 more
core   +1 more source

Pertussis toxin treatment increases glutamate release and dihydropyridine binding sites in cultured rat cerebellar granule neurons [PDF]

open access: yes, 1993
: This study was designed to examine the ability of pertussis toxin to block various responses due to (-)-baclofen in cultured cerebellar granule neurons of the rat.

core  

Prevention of pertussis: An unresolved problem

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Pertussis is a highly contagious respiratory disease caused by Bordetella pertussis. However, after the introduction of the whole-cell pertussis vaccine (wP), the annual incidence rates of the disease progressively declined.
Susanna Esposito, Nicola Principi
doaj   +1 more source

Comparison of nasopharyngeal culture, polymerase chain reaction (PCR) and serological test for diagnosis of pertussis

open access: yesThe Turkish Journal of Pediatrics, 2009
This prospective study, which was designed to compare nasopharyngeal culture, polymerase chain reaction (PCR) and serology in the diagnosis of pertussis, covered 35 children aged between 0 and 16 who were admitted to Hacettepe University Ihsan ...
Ali Bülent Cengiz   +5 more
doaj  

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