Results 91 to 100 of about 32,826 (199)

PENGARUH pH ELUEN TERHADAP HASIL DESALTING CRUDE PERTUSSIS TOXIN (PT) DAN FILAMENTOUS HEMAGGLUTININ (FHA) DARI Bordetella pertussis [PDF]

open access: yes, 2014
Optimizing desalting crude process of PT and FHA using sephadex G-25 as intermediate purification phase for PT and FHA as acellular pertussis vaccine components has been developed.
Neni Nurainy   +3 more
core  

Pertussis toxin uncouples dopamine agonist inhibition of prolactin release

open access: yes, 1983
Pertussis toxin, a protein exotoxin produced by Bordetella pertussis, markedly reduced or eliminated the ability of dopamine or the dopamine agonist bromocriptine to inhibit prolactin release from anterior pituitary cells in vitro.
E. L. Hewlett   +3 more
core   +1 more source

Characterization of new approaches to inhibit Pertussis toxin based on human peptides and cellular chaperone inhibitors

open access: yes
Pertussis, also known as whooping cough, is a contagious respiratory disease, caused by a bacterial infection with Bordetella pertussis. Pertussis is characterized by paroxysmal coughing, which can lead to severe complications and even death, especially ...
Kling, Carolin
core   +1 more source

Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells

open access: yesmBio, 2019
Monocytes arriving at the site of infection differentiate into functional effector macrophages to replenish the resident sentinel cells. Bordetella pertussis, the pertussis agent, secretes an adenylate cyclase toxin-hemolysin (CyaA) that binds myeloid ...
Jawid Nazir Ahmad   +6 more
doaj   +1 more source

Pertussis Toxin or Antigen

open access: yesExperimental Biology and Medicine, 1933
Mishulow, Mowry and Scott1 demonstrated that exotoxic filtrates could be obtained from whooping cough cultures. They planted their organisms on chocolate agar over which they had poured a small amount of horse serum-beef heart broth. The small amount of diluent made the harvest of toxin necessarily small. On the other hand, Craster and Smith2 mentioned
J. A. Toomey, J. E. McClelland
openaire   +1 more source

Comparative study of a whole-cell pertussis vaccine and a recombinant acellular pertussis vaccine.

open access: yes, 1994
The safety and immunogenicity of an acellular pertussis vaccine containing the genetically detoxified pertussis toxin PT-9K/129G, filamentous hemagglutinin, and pertactin, together with diphtheria and tetanus toxoids, were compared with those of a whole ...
RAPPUOLI R. AND THE ITALIAN MULTICENTER GROUP FOR THE STUDY OF RECOMBINANT ACELLULAR PERTUSSIS VACCINE   +12 more
core  

Effect of pertussis toxin on hormonal responsiveness of rat hepatocytes

open access: yes, 1983
The ureogenic action of epinephrine in hepatocytes from normal adult rats is mediated through activation of α1-adrenoceptors. β-Adrenoceptors in addition to α1-adrenoceptors, became involved in mediating this effect in cells from animals treated with ...
J. Adolfo García-Sáinz   +5 more
core   +1 more source

Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunity.

open access: yesPLoS ONE, 2011
Pertussis (whooping cough) is frequently complicated by concomitant infections with respiratory viruses. Here we report the effect of Bordetella pertussis infection on subsequent influenza virus (PR8) infection in mouse models and the role of pertussis ...
Victor I Ayala   +4 more
doaj   +1 more source

Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride

open access: yes, 1990
Fluoride is a direct activator of G-proteins. In isolated rings of canine coronary artery, fluoride caused relaxation of rings with endothelium, but only slight contraction of rings denuded of endothelium.
Flavahan, NA, Vanhoutte, PM
core   +1 more source

Pertussis toxin reverses prostaglandin E2- and somatostatin-induced inhibition of rat parietal cell H(+)-production

open access: yes, 1992
In enzymatically dispersed enriched rat parietal cells we studied the effect of pertussis toxin on prostaglandin E2 (PGE2)- or somatostatin-induced inhibition of H(+)-production.
Rosenthal, W.   +5 more
core   +1 more source

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