Results 81 to 90 of about 33,335 (199)

Pertussis toxin inhibits endothelium-dependent relaxations evoked by fluoride [PDF]

, 1990
Fluoride is a direct activator of G-proteins. In isolated rings of canine coronary artery, fluoride caused relaxation of rings with endothelium, but only slight contraction of rings denuded of endothelium.
Flavahan, NA, Vanhoutte, PM
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1673-1685, August 2026.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Pertussis toxin reverses prostaglandin E2- and somatostatin-induced inhibition of rat parietal cell H(+)-production [PDF]

, 1992
In enzymatically dispersed enriched rat parietal cells we studied the effect of pertussis toxin on prostaglandin E2 (PGE2)- or somatostatin-induced inhibition of H(+)-production.
Rosenthal, W., Classen, M., Schusdziarra, V., Schmidtler, J., Schepp, W., Offermanns, S.   +5 more
core   +1 more source

Seroprevalence of diphtheria and pertussis immunoglobulin G among children with pneumonia in Ji’nan, China

BMC Pediatrics, 2018
Background Vaccination is still one of the most important methods to control and prevent childhood infections including diphtheria and pertussis. This study evaluated the level of diphtheria (DT) and pertussis (PT)-related antibodies among children with ...
Qinghong Meng, Lijun Li, Wei Shi, Qing Wang, Mingjie Ding, Yanqin Liu, Xiang Ma, Kaihu Yao   +7 more
doaj   +1 more source

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain

Iranian Journal of Microbiology, 2020
Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati, Ashraf Mohabati Mobarez, Seyed Davar Siadat, Mojtaba Noofeli   +3 more
doaj   +1 more source

Pyruvate Kinase M2 Upregulation Is Associated With Guillain–Barré Syndrome Risk and Immune Dysregulation: Insights From Mendelian Randomization and the Experimental Autoimmune Neuritis Model

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Objective This study aimed to investigate the potential involvement of pyruvate kinase M2 (PKM2) in the pathogenesis of Guillain–Barré syndrome (GBS). Methods Mendelian randomization (MR) analysis was used to evaluate the causal association between PKM2 expression and GBS susceptibility, with mediation analysis performed to explore immune cell‐
Shuping Liu, Huiying Lu, Yuge Kang, Zheman Xiao, Qian Min, Yi Dong   +5 more
wiley   +1 more source

INTRATHECAL PERTUSSIS TOXIN INDUCES THERMAL HYPERALGESIA: INVOLVEMENT OF EXCITATORY AND INHIBITORY AMINO ACIDS [PDF]

, 2020
-Intrathecal pertussis toxin injection has been used as a neuropathic pain model. In the present study, its effects on cerebrospinal fluid biochemistry and nociceptive behavioral expression were examined in rats.
C.-S Wong, Y.-C Chang, J.-Y Chen, Z.-H Wen, L.-C Yang, J.-J Wang, C.-H Hsing   +6 more
core  

Pertussis toxin inhibits somatostatin-induced K+ conductance in human pituitary tumor cells [PDF]

, 1987
The effect of pertussis toxin on somatostatin-induced K+ current was examined in dissociated human pituitary tumor cells obtained from two acromegalic patients.
N. Yamashita, I. Kojima, N. Shibuya, E. Ogata   +3 more
core   +1 more source

Understanding the Epidemiology of Pertussis in Denmark

Acta Paediatrica, EarlyView.
Tine Dalby, Aoife Ronayne, Peter Henrik Andersen   +2 more
wiley   +1 more source

The cGAS–STING Pathway Drives Astrocyte‐Mediated Demyelination in Multiple Sclerosis Through Clusterin Secretion

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
In multiple sclerosis, astrocytes detect extracellular DNA via the cGAS–STING pathway, triggering Clusterin secretion that induces oligodendrocyte apoptosis and demyelination. Pharmacological STING inhibition with H‐151 suppresses this neurotoxic cascade, preserves myelin integrity, and ameliorates clinical disability in experimental autoimmune ...
Shengfei Hu, Xia Xiao, Xi Cheng, Yiying Huang, Tingting Cui, Shishi Shen, Chunping Cui, Li Xiao, Hanzhang Tan, Wei Qiu, Yipeng Zhao, Rui Li   +11 more
wiley   +1 more source