Results 1 to 10 of about 110,621 (200)

Dendrimer-based contrast agents for PET imaging [PDF]

Drug Delivery, 2017
Positron emission tomography (PET) imaging offers physiological and biological information through the in vivo distribution of PET agents for disease diagnosis, therapy monitoring and prognosis evaluation.
Lingzhou Zhao, Xiangyang Shi, Jinhua Zhao   +2 more
doaj   +5 more sources

The Performance of FDA-Approved PET Imaging Agents in the Detection of Prostate Cancer [PDF]

Biomedicines, 2022
Positron emission tomography (PET) incorporated with X-ray computed tomography (PET/CT) or magnetic resonance imaging (PET/MRI) is increasingly being used as a diagnostic tool for prostate cancer (PCa).
Mei Li, Roman Zelchan, Anna Orlova
doaj   +6 more sources

Emerging PET Imaging Agents and Targeted Radioligand Therapy: A Review of Clinical Applications and Trials [PDF]

Tomography
Targeted radioligand therapy (RLT) is an emerging field in anticancer therapeutics with great potential across tumor types and stages of disease. While much progress has focused on agents targeting somatostatin receptors and prostate-specific membrane ...
Maierdan Palihati, Jeeban Paul Das, Randy Yeh, Kathleen Capaccione   +3 more
doaj   +3 more sources

Translating Molecules into Imaging—The Development of New PET Tracers for Patients with Melanoma

Diagnostics, 2022
Melanoma is a deadly disease that often exhibits relentless progression and can have both early and late metastases. Recent advances in immunotherapy and targeted therapy have dramatically increased patient survival for patients with melanoma.
Laetitia Vercellino, Dorine de Jong, Laurent Dercle, Benoit Hosten, Brian Braumuller, Jeeban Paul Das, Aileen Deng, Antoine Moya-Plana, Camry A’Keen, Randy Yeh, Pascal Merlet, Barouyr Baroudjian, Mary M. Salvatore, Kathleen M. Capaccione   +13 more
doaj   +2 more sources

Progress of PET Imaging Agents for Cardiovascular Diseases

Journal of Isotopes, 2018
Positron emission tomography ( PET) imaging has successfully allowed the noninvasive detection of cardiovascular disease and shows good clinical application prospects. Development and translation application of various imaging agents furtherly enable PET
MA Hui1;LIANG Hong1;XU Wan-bang2;TANG Gang-hua1
doaj   +2 more sources

Revolutionizing Prostate Cancer Detection: The Role of Approved PSMA-PET Imaging Agents. [PDF]

Pharmaceuticals (Basel)
Locametz®/Illuccix®/GozellixTM (Novartis AG (Basel, Switzerland) and Telix Pharmaceuticals, Ltd. (Melbourne, Australia), all three [68Ga]Ga-PSMA-11), Pylarify®/Pylclari® (Progenics Pharmaceuticals, Inc. (New York, USA) and Curium PET France SA (Paris, France), both [18F]DCFPyL), Radelumin® (ABX GmbH (Radeberg, Germany), [18F]PSMA-1007), and Posluma ...
Hennrich U, Wagner L, Taş H, Kovacs L, Benešová-Schäfer M.   +4 more
europepmc   +4 more sources

Cyclic Peptides Targeting Granzyme B: Potential Applications as PET Imaging Agents. [PDF]

ACS Med Chem Lett
This patent application pertains to macrocyclic peptides and their radiolabeled derivatives, generally represented by Formula I. These compounds exhibit selective binding to Granzyme B (GzmB) and hold the potential for imaging disease or disorders associated with elevated GzmB levels.
Hu QL, Liang SH.
europepmc   +3 more sources

Tellurium-118 as a novel radionuclide for long-term positron emission tomography [PDF]

Scientific Reports
Positron emission tomography (PET) is a powerful imaging modality that tracks positron-emitting radionuclides, enabling non-invasive and high-resolution visualization of biological targets and processes.
Sotaro Miyao, Toshimitsu Momose, Masako Kawabata, Yuki Mitsuya, Atsuko Nakanishi Ozeki, Arisa Hayashi, Xindi Qiu, Yousuke Kanayama, Hiromitsu Haba, Izumi O. Umeda, Jaewoong Jang, Youichiro Wada, Nobuyoshi Akimitsu, Hiroyuki Takahashi   +13 more
doaj   +2 more sources

On the Dissociation Pathways of Copper Complexes Relevant as Pet Imaging Agents

SSRN Electronic Journal, 2022
Several bifunctional chelators have been synthesized in the last years for the development of new 64Cu-based PET agents for in vivo imaging. When designing a metal-based PET probe, it is important to achieve high stability and kinetic inertness once the radioisotope is coordinated. Different competitive assays are commonly used to evaluate the possible
Uzal-Varela, Rocío, Patinec, Véronique, Tripier, Raphaël, Valencia, Laura, Maneiro, Marcelino, Canle, Moisés, Platas-Iglesias, Carlos, Esteban-Gómez, David, Iglesias, Emilia   +8 more
openaire   +4 more sources

Peptide-based PET imaging agent of tumor TIGIT expression

EJNMMI Research, 2023
Abstract Background Accumulating studies have demonstrated that elevated TIGIT expression in tumor microenvironment correlates with better therapeutic response to TIGIT-based immunotherapy in pre-clinical studies. Therefore, a non-invasive method to detect tumor TIGIT expression is crucial to predict the therapeutic ...
Dinghu Weng, Rong Guo, Ziyang Zhu, Yu Gao, Rui An, Xiuman Zhou   +5 more
openaire   +3 more sources