Results 51 to 60 of about 449,349 (233)
A PET imaging agent for evaluating PARP-1 expression in ovarian cancer [PDF]
Journal of Clinical Investigation, 2018 Poly(ADP-ribose) polymerase (PARP) inhibitors are effective in a broad population of patients with ovarian cancer; however, resistance caused by low enzyme expression of the drug target PARP-1 remains to be clinically evaluated in this context. We hypothesize that PARP-1 expression is variable in ovarian cancer and can be quantified in primary and ...
Mehran Makvandi +17 more
openaire +2 more sources
Metal-Based Complexes as Pharmaceuticals for Molecular Imaging of the Liver
Pharmaceuticals, 2019 This article reviews the use of metal complexes as contrast agents (CA) and radiopharmaceuticals for the anatomical and functional imaging of the liver.
Julia Greiser +2 more
doaj +1 more source
Test–Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18 [PDF]
Journal of Nuclear Medicine, 2017 Alzheimer disease (AD) is characterized by β-amyloid (Aβ) plaques and tau neurofibrillary tangles. There are several PET imaging biomarkers for Aβ including 11C-PiB and 18F-florbetapir. Recently, PET tracers for tau neurofibrillary tangles have become available and have shown utility in detection and monitoring of neurofibrillary pathology over time ...
Michael D, Devous +10 more
openaire +2 more sources
Radiolabeled Iron Oxide Nanoparticles as Dual Modality Contrast Agents in SPECT/MRI and PET/MRI
Nanomaterials, 2023 During the last decades, the utilization of imaging modalities such as single photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) in every day clinical practice has enabled clinicians to ...
Maria-Argyro Karageorgou +3 more
doaj +1 more source
Update on the Use of PET/MRI Contrast Agents and Tracers in Brain Oncology: A Systematic Review
International Journal of Nanomedicine, 2022 Alessio Smeraldo,1– 3,* Alfonso Maria Ponsiglione,1,* Andrea Soricelli,4 Paolo Antonio Netti,1– 3 Enza Torino1– 3 1Department of Chemical, Materials and Production Engineering, University of Naples “Federico II”, Naples, 80125, Italy ...
Smeraldo A +4 more
doaj
Diagnostic imaging for hepatocellular carcinoma [PDF]
, 2019 Hepatocellular carcinoma (HCC) occurs mostly in individuals with cirrhosis, which is why the guidelines of the most important scientific societies indicate that these patients are included in surveillance programs through the repetition of an ultrasound ...
DE SANTIS, Adriano
core +1 more source
EJNMMI Research, 2021 Background Animal brain functions evaluated by in vivo imaging under anesthesia can be affected by anesthetic agents, resulting in incorrect assessment of physiological brain function.
Chie Suzuki +2 more
doaj +1 more source
GBM radiosensitizers: dead in the water…or just the beginning? [PDF]
, 2017 The finding that most GBMs recur either near or within the primary site after radiotherapy has fueled great interest in the development of radiosensitizers to enhance local control.
Bindra, Ranjit S. +3 more
core +1 more source
F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain.
Journal of Medicinal Chemistry, 2005 Imaging agents targeting beta-amyloid (Abeta) may be useful for diagnosis and treatment of patients with Alzheimer's disease (AD). Compounds 3e and 4e are fluorinated stilbene derivatives displaying high binding affinities for Abeta plaques in AD brain ...
Wei Zhang +5 more
semanticscholar +1 more source
Synthesis, Preclinical Evaluation, and a Pilot Clinical PET Imaging Study of 68Ga-Labeled FAPI Dimer
Journal of Nuclear Medicine, 2021 Visual Abstract Cancer-associated fibroblasts (CAFs) are crucial components of the tumor microenvironment. Fibroblast activation protein (FAP) is overexpressed in CAFs. FAP-targeted molecular imaging agents, including the FAP inhibitors (FAPIs) 04 and 46,
Liang Zhao +10 more
semanticscholar +1 more source