Results 81 to 90 of about 11,617 (181)

Recent advances in classic heparin-induced thrombocytopenia (HIT), autoimmune HIT, spontaneous HIT, and vaccine-induced immune thrombotic thrombocytopenia

Bleeding, Thrombosis and Vascular Biology
Anti-platelet factor 4 (PF4) disorders are a group of platelet-consumptive disorders characterized by platelet-activating antibodies against PF4, thrombocytopenia and an increased risk of thrombosis.
Bianca Clerici, Mariangela Scavone, Gian Marco Podda   +2 more
doaj   +1 more source

PF4 as a Regenerative Signal

This paper expands a systems‑level regenerative immunology framework by introducing Platelet Factor 4 (PF4) as a mechanistic co‑signal for immune‑guided tissue repair. Building on prior work in TH17 plasticity and TH22 stabilization, the paper explores how PF4’s hematopoietic and anti‑inflammatory properties can reinforce long‑term immune recalibration.
openaire   +1 more source

Anti‐PF4 disorders: Pathogenesis, diagnosis and treatment

British Journal of Haematology
SummaryPlatelet factor 4 (PF4) is a cationic protein, able to form complexes with negatively charged molecules upon its self‐assembly into PF4 tetramers. The targeting of these PF4 complexes by immunoglobulin G (IgG) antibodies underlies anti‐PF4 disorders such as heparin‐induced thrombocytopenia (HIT) and Vaccine‐Induced Immune Thrombocytopenia and ...
Megan V. Preece, Devi V. Pathak, Mike Laffan, Deepa J. Arachchillage   +3 more
openaire   +2 more sources

Case Report: Anti-platelet factor 4 -mediated immunothrombosis in a patient with ANCA vasculitis – a shared mechanism of NETosis

Frontiers in Immunology
Anti-platelet factor 4 (PF4) immunothrombosis is characterized by thrombocytopenia, thrombosis and enhanced NETosis and has been described in the absence of prior heparin exposure.
Lital Remez-Gabay, Lital Remez-Gabay, Olga Vdovich, Olga Vdovich, Luiza Akria, Luiza Akria, Etty Kruzel-Davila, Etty Kruzel-Davila, Etty Kruzel-Davila   +8 more
doaj   +1 more source

PF4 Gene [PDF]

, 2020
openaire   +1 more source

PF4 [PDF]

, 2019
openaire   +1 more source

PF4 wt Allele [PDF]

, 2020
openaire   +1 more source

Antiphospholipid and anti‐PF4 antibodies: an association affecting anti‐PF4/heparin assay analysis [PDF]

Journal of Thrombosis and Haemostasis, 2009
openaire   +2 more sources

The hidden threat: understanding anti-PF4 disorders without proximate heparin exposure. [PDF]

Front Immunol
Liu Z, Li Y, Ma L, Wang X, Cui Y.
europepmc   +1 more source

Induction of the filamentous prophage, Pf4, is conditionally regulated by PA3572 (<i>difP</i>) in <i>Pseudomonas aeruginosa</i> biofilms. [PDF]

Microbiology (Reading)
Patell SZ, Welch M.
europepmc   +1 more source