Results 61 to 70 of about 11,617 (181)

Anti‐platelet factor 4/heparin antibodies in patients with Hantaan virus infection

Research and Practice in Thrombosis and Haemostasis, 2022
Background Hemorrhagic fever with renal syndrome (HFRS) induced by Hantaan virus infection and heparin‐induced thrombocytopenia (HIT) are associated with symptoms such as thrombocytopenia and thrombosis.
Meng Wang, Chun‐mei Zhang, Ying Ma, Kang Tang, Xi‐yue Zhang, Xiao‐zhou Jia, Hai‐feng Hu, Ran Zhuang, Bo‐quan Jin, Yu‐si Zhang, Yun Zhang   +10 more
doaj   +1 more source

Late Cenozoic Sediment Provenance in the Northern Canterbury Basin, Aotearoa New Zealand

New Zealand Journal of Geology and Geophysics, Volume 69, Issue 4, December 2026.
Late Cenozoic strata of the northern Canterbury Basin record uplift and erosion of mountain ranges adjacent to the transition from oblique subduction to strike‐slip on the Australian–Pacific plate boundary. Using the provenance of conglomerate clasts and sandstone samples, we reconstruct sediment transport pathways and, by inference, exhumation and ...
Matthew O. Parker, Kari N. Bassett, Matthew W. Sagar, Alexander R. L. Nichols, Greg H. Browne, Andrew Nicol   +5 more
wiley   +1 more source

Prevalence of anti–platelet factor 4/polyanionic antibodies after COVID‐19 vaccination with ChAdOx1 nCoV‐19 and CoronaVac in Thais

Research and Practice in Thrombosis and Haemostasis, 2021
Introduction Vaccine‐induced thrombotic thrombocytopenia (VITT) has been reported after vaccination with the adenoviral vector coronavirus disease 2019 (COVID‐19) vaccine ChAdOx1 nCoV‐19 in European countries.
Phichchapha Noikongdee, Pornnapa Police, Tichayapa Phojanasenee, Pichika Chantrathammachart, Pimjai Niparuck, Teeraya Puavilai, Angsana Phuphuakrat, Pantep Angchaisuksiri, Kochawan Boonyawat   +8 more
doaj   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Identification of SORT1 as a Key Regulator of Antigen Presentation in CD16+ Monocytes During Septic Shock via Multi‐Omics and In Silico Gene Knockout Analysis

Immunity, Inflammation and Disease, Volume 14, Issue 10, October 2026.
ABSTRACT Objective This study aimed to screen and identify hub genes correlated with septic shock through integrative analyses of bulk transcriptomics, machine learning, weighted gene co‐expression network analysis (WGCNA), single‐cell transcriptomics, and in silico gene knockout, and further dissect their underlying immunoregulatory mechanisms ...
Shulu Wu, Jiaying Zhang, Shiqi Guo, Yuting Hu, Hui Shen, Yingjie Xu, Bining Yang   +6 more
wiley   +1 more source

Pancreatic Cancer Disrupts Circadian Patterns of Gene Expression in Cardiorespiratory Muscles

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Cancer cachexia, a debilitating syndrome characterized by muscle wasting, significantly impacts survival in gastrointestinal cancers like pancreatic cancer. Emerging evidence suggests a link between cancer cachexia and disrupted circadian rhythms in peripheral tissues, including locomotor muscles. However, circadian dysregulation in
Jeremy B. Ducharme, Martin M. Schonk, Miguel A. Gutierrez‐Monreal, Leonardo F. Ferreira, Karyn A. Esser, Andrew R. Judge, Sarah M. Judge   +6 more
wiley   +1 more source

The Inovirus Pf4 Triggers Antiviral Responses and Disrupts the Proliferation of Airway Basal Epithelial Cells

Viruses
Background: The inovirus Pf4 is a lysogenic bacteriophage of Pseudomonas aeruginosa (Pa). People with Cystic Fibrosis (pwCF) experience chronic airway infection with Pa and a significant proportion have high numbers of Pf4 in their airway secretions ...
Medeea C. Popescu, Naomi L. Haddock, Elizabeth B. Burgener, Laura S. Rojas-Hernandez, Gernot Kaber, Aviv Hargil, Paul L. Bollyky, Carlos E. Milla   +7 more
doaj   +1 more source

Tissue‐Specific Isolation of Hepatocyte Extracellular Vesicles From Human Plasma Enables Tissue‐Resolved Proteomic and miRNA Profiling

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
ABSTRACT Tissue‐specific resolution remains a critical barrier in liquid biopsy for precision medicine. To address this, we developed NEXPLOR (Novel EXtracellular vesicle PopuLation Omics Revealer), an immunoaffinity platform enabling selective enrichment of circulating tissue‐specific extracellular vesicles (TS‐EVs), demonstrated here for liver ...
Ricardo Figueiras, Susana Vagueiro, Raissa Kay, Elnaz Persia, Roger de Alwis, Razan Hijazi, Brian Davidson, Kristine von Bargen, Pierre Arsène, Tomás Dias   +9 more
wiley   +1 more source

Regulation of filamentous phage Pf4 activation by oxidative stress in Pseudomonas aeruginosa

mLife
The filamentous prophage Pf4 is activated to produce phage virions during Pseudomonas aeruginosa biofilm formation, a process crucial for maintaining biofilm architecture and enhancing pathogenicity.
Zixian Huang, Xinqiao Zhang, Shituan Lin, Jiayu Gu, Cong Liu, Mingzhang Wen, Yunxue Guo   +6 more
doaj   +1 more source

Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny.

PLoS ONE, 2012
The development of a megakaryocyte lineage specific Cre deleter, using the Pf4 (CXCL4) promoter (Pf4-Cre), was a significant step forward in the specific analysis of platelet and megakaryocyte cell biology.
Simon D J Calaminus, Amelie V Guitart, Amy Sinclair, Hannah Schachtner, Steve P Watson, Tessa L Holyoake, Kamil R Kranc, Laura M Machesky   +7 more
doaj   +1 more source