Results 121 to 130 of about 4,262 (206)

Peptide accumulation co-segregates with the pfcrt locus on Chromosome 7.

, 2014
A genetic recombination map is plotted versus the mean pfcrt-linked peptide level observed with each clone. Progeny carrying the Dd2 (red) chloroquine resistant allele at the pfcrt locus show higher levels of peptides than progeny carrying the HB3 ...
Ian A. Lewis (505358), Mark Wacker (505359), Kellen L. Olszewski (238867), Michael T. Ferdig (93077), Simon A. Cobbold (505360), Katelynn S. Baska (505361), Asako Tan (271085), Manuel Llinás (14834)   +7 more
core   +1 more source

Rapid and supersensitive allele detection of Plasmodium falciparum chloroquine resistance via a Pyrococcus furiosus argonaute-triggered dual-signal biosensing platform

Parasites & Vectors
Background Malaria remains a serious public health problem worldwide, particularly in Africa. Resistance to antimalarial drugs is an essential issue for malaria control and elimination.
Liying Chen, Wencheng Chen, Huagui Wei, Wenai Lin, Cheng Zhang, Hongfei Hu, Chunfang Wang, Jiangtao Chen, Xueyan Liang, Daiqian Zhu, Junli Wang, Zongyun Lin, Yuxia Wei, Jian Li, Min Lin   +14 more
doaj   +1 more source

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola.

, 2009
OBJECTIVES: To assess the extent of drug resistance in Uige through molecular genetic analysis and to test whether the dhfr triple mutant alleles present in Angola are of southeast Asian origin.
Inojosa WO, Roper C, Bisoffi, Zeno, Bisoffi Z, Ord, Rosalynn, Roper, Cally, Abel PM, Severini C, Pisani, Vincenzo, Matondo A, Warhurst DC, Pisani V, Pearce RJ, Matondo, Alexandre, Warhurst, David C, Severini, Carlo, Menegon M, Menegon, Michela, Inojosa, Walter O, Abel, Paulo M, Majori, Giancarlo, Majori G, Ord R, Pearce, Richard J   +23 more
core   +1 more source

CQ IC₅₀s, PfCRT and Pgh1 polymorphisms, and pfmdr1 copy number.

, 2014
CQ IC50s, PfCRT and Pgh1 polymorphisms, and pfmdr1 copy number.
François H. Nosten (315303), Bruce Russell (35525), Martin J. Lear (649334), Kit-Ying Choy (649333), Yan Quan Lee (649331), Laurent Rénia (2935842), Rossarin Suwanarusk (35524), Kevin S. W. Tan (160329), Larry M. C. Chow (649335), Cheryl C. Y. Loh (649330), Kitti W. K. Chan (649332)   +10 more
core   +1 more source

New haplotypes of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene among chloroquine-resistant parasite isolates

, 2003
Mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene were examined to assess their associations with chloroquine resistance in clinical samples from Armopa (Papua) and Papua New Guinea.
Jessica McGuire (20016762), K Baird (9872564), Nagesh Hadya (20016747), G Casey (11161569), K Rieckmann (20016750), B Laksana (20016756), C J (20016759), D Fryauff (20016753)   +7 more
core   +1 more source

Plasmodium falciparum chloroquine resistance transporter (PfCRT) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Unraveling Key Chloroquine Resistance-Associated Alleles Among Plasmodium falciparum Isolates in South Darfur State, Sudan Twelve Years After Drug Withdrawal

Infection and Drug Resistance
Abdalmoneim M Magboul,1 Bakri YM Nour,2 Abdelhakam G Tamomh,1 Rashad Abdul-Ghani,3,4 Sayed Mustafa Albushra,5 Hanan Babiker Eltahir6 1Department of Parasitology & Medical Entomology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi,
Magboul AM, Nour BY, Tamomh AG, Abdul-Ghani R, Albushra SM, Eltahir HB   +5 more
doaj  

In vivo selection of **Plasmodium falciparum** Pfcrt and Pfmdr1 variants by artemether-lumefantrine and dihydroartemisinin-piperaquine in Burkina Faso

, 2015
: Plasmodium falciparum Pfcrt-76 and Pfmdr1-86 gene polymorphisms were determined during a clinical trial in Burkina Faso comparing the efficacies of dihydroartemisinin-piperaquine (DHA-PPQ) and artemether-lumefantrine (AL).
Mbonye, Martin, Van geertruyden, Jean-Pierre, Baraka, Vito, Tinto, Halidou, Valea, Innocent, Delgado Ratto, Christopher, et al.   +6 more
core  

Molecular Surveillance of Antimalarial Drug Resistance-Associated Mutations in <i>P. falciparum</i> Imported from Africa into Guangdong Province, China, 2023-2025. [PDF]

Pathogens
Chen L, Mao Q, Wu, Liu J, Zhang J, Lu W, Peng M, Chen Y, Wang J, Chen J, Shi M.   +10 more
europepmc   +1 more source

New haplotypes of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene among chloroquine-resistant parasite isolates.

, 2016
Mutations in the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene were examined to assess their associations with chloroquine resistance in clinical samples from Armopa (Papua) and Papua New Guinea.

core