Results 11 to 20 of about 122,171 (336)
BJUI Compass, Volume 4, Issue 1, Page 44-58, January 2023., 2023 Abstract Metformin, the first line pharmacotherapy for type 2 diabetes has demonstrated favourable effects in prostate cancer (PCa) across a range of studies evaluating PCa patient outcomes amongst metformin users. However, a lack of rigorously conducted prospective studies has stalled clinical use in this setting.
Nan Fang Wang +3 more
wiley +1 more source
OncoImmunology, 2021 The similarity of stromal-like Wilms tumor (str-WT) cells with mesenchymal stem cells (MSC), suggests their relevant role in the interplay with immune cells in the tumor microenvironment. We investigated the interaction between str-WT cells and NK cells.
Claudia Cantoni +10 more
doaj +1 more source
BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022 Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley +1 more source
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
BioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022 Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo +2 more
wiley +1 more source
Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]
, 1987 The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M. +3 more
core +1 more source
Experimental Biology and Medicine, 1983 The angiogenic capability of PGE2 was tested by implanting pellets of an ethylene vinyl acetate slow release polymer containing PGE2 on the chorioallantoic membrane of 8-day-old chicken embryos. Elvax pellets releasing approximately 0.2, 2.0, or 20 ng/day PGE2 were found to induce neovascular responses.
Robert Auerbach, David M. Form
openaire +3 more sources
Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]
, 2007 Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico +8 more
core +1 more source
The PGE2-Stat3 connection in cardiac hypertrophy [PDF]
Cardiovascular Research, 2007 See article by Frias et al. [6] (pages 57–65) in this issue. In vivo cardiac hypertrophy is a slow process in which the myocytes increase in size in response to increased workload due to either an increase in hemodynamic load or to a loss of functional myocytes. Although the mechanical load has long been recognized as the most powerful hypertrophic
Schaub, Marcus C, Hefti, Martin A
openaire +3 more sources
Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells. [PDF]
, 2014 Prostaglandin E2 (PGE2), a pleiotropic immunomodulatory molecule, and its free radical catalyzed isoform, iso-PGE2, are frequently elevated in the context of cancer and chronic infection.
Chou, Jennifer P +4 more
core +2 more sources
Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]
, 2006 We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C. +15 more
core +4 more sources