Results 51 to 60 of about 531,900 (348)

The Safety and Toxicity of Phage Therapy: A Review of Animal and Clinical Studies

Viruses, 2021
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and humans have been completed over the last two decades.
Dan Liu, Jonas D. Van Belleghem, Christiaan R. de Vries, Elizabeth B. Burgener, Qingquan Chen, R. Manasherob, J. Aronson, D. Amanatullah, P. Tamma, G. Suh   +9 more
semanticscholar   +1 more source

Endolysin Regulation in Phage Mu Lysis

mBio, 2022
Bacteriophage Mu is a paradigm coliphage studied mainly because of its use of transposition for genome replication. However, in extensive nonsense mutant screens, only one lysis gene has been identified, the endolysin gp22.
Jake S. Chamblee, Jolene Ramsey, Yi Chen, Lori T. Maddox, Curtis Ross, Kam H. To, Jesse L. Cahill, Ry Young   +7 more
doaj   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Alicia Aguilar, Altschul, Arturo Talavera, Beales, Beckmann, Bosch, Burritt, Burritt, Clark, Cohen, Collins, Cuthbert, David I. Stott, de la Cruz, Delmastro, Ela M. Perez, Emini, Enshell-Seijffers, Felici, Folgori, Folgori, Frank Camacho, Gomara, Hollinger, Hoogenboon, Irving, Lemon, Lemon, Lemon, Lemon, Lemon, Lemon, Marston, Martin, Mattioli, Nainan, Neduva, Nevis Amin, Osmany G. Larralde, Partidos, Perea, Perez, Ping, Ping, Prezzi, Raiza Martinez, Reed, Sambrook, Scholfield, Stapleton, Stapleton, Stapleton, Verdaguer, Wan, Zhang   +54 more
core   +1 more source

New Insights into the Structure and Assembly of Bacteriophage P1

Viruses, 2022
Bacteriophage P1 is the premier transducing phage of E. coli. Despite its prominence in advancing E. coli genetics, modern molecular techniques have not been applied to thoroughly understand P1 structure.
Miguel F. Gonzales, Denish K. Piya, Brian Koehler, Kailun Zhang, Zihao Yu, Lanying Zeng, Jason J. Gill   +6 more
doaj   +1 more source

The green production of eco-friendly silver with cobalt ferrite nanocomposite using Citrus limon extract

Results in Chemistry, 2023
This paper reveals a novel and greener strategy to biosynthesize Cobalt-Ferrite-Silver trimetallic nanoparticles (Co-Fe-AgNPs) using the Citrus limon extract as a bio-reducing agent. Depending on the Transmission and Scanning Electron Microscopy (TEM and
Abdallah S. Abdelsattar, Azza G. Kamel, Ayman El-Shibiny   +2 more
doaj   +1 more source

Phage Therapy: A Renewed Approach to Combat Antibiotic-Resistant Bacteria.

Cell Host and Microbe, 2019
Phage therapy, long overshadowed by chemical antibiotics, is garnering renewed interest in Western medicine. This stems from the rise in frequency of multi-drug-resistant bacterial infections in humans.
K. Kortright, B. Chan, J. Koff, P. Turner   +3 more
semanticscholar   +1 more source

Phage-Plasmids Spread Antibiotic Resistance Genes through Infection and Lysogenic Conversion

bioRxiv, 2022
The dissemination of antimicrobial resistance is a major threat to global health. Here, we show that a group of temperate bacterial viruses (phages), termed phage-plasmids, commonly encode different and multiple types of resistance genes of high clinical
E. Pfeifer, R. Bonnin, E. Rocha
semanticscholar   +1 more source

Recent Advances in Structural Studies of Single-Stranded RNA Bacteriophages

Viruses, 2023
Positive-sense single-stranded RNA (ssRNA) bacteriophages (phages) were first isolated six decades ago. Since then, extensive research has been conducted on these ssRNA phages, particularly those infecting E. coli.
Jirapat Thongchol, Zachary Lill, Zachary Hoover, Junjie Zhang   +3 more
doaj   +1 more source

Isolation and Characterization of Bacteriophage ZCSE6 against Salmonella spp.: Phage Application in Milk

Biologics, 2021
Food safety is very important in the food industry as most pathogenic bacteria can cause food-borne diseases and negatively affect public health.
Abdallah S. Abdelsattar, Anan Safwat, Rana Nofal, Amera Elsayed, Salsabil Makky, Ayman El-Shibiny   +5 more
doaj   +1 more source

A Comprehensive Review on Phage Therapy and Phage-Based Drug Development

Antibiotics
Phage therapy, the use of bacteriophages (phages) to treat bacterial infections, is regaining momentum as a promising weapon against the rising threat of multidrug-resistant (MDR) bacteria.
Longzhu Cui, Shinya Watanabe, Kazuhiko Miyanaga, Kotaro Kiga, Teppei Sasahara, Y. Aiba, Xin-Ee Tan, Srivani Veeranarayanan, Kanate Thitiananpakorn, Huong Minh Nguyen, D. Wannigama   +10 more
semanticscholar   +1 more source