Results 101 to 110 of about 149,596 (212)

Glycolytic metabolism of CD8+ T‐cells affects susceptibility to human leukocyte antigen‐mediated abacavir‐induced hypersensitivity

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida, Yuchen Sun, Noriaki Arakawa, Takuya Hirao, Tadahaya Mizuno, Shigeki Aoki, Kousei Ito, Yoshihiro Hayakawa   +7 more
wiley   +1 more source

Core Lipopolysaccharide-Specific Phage SSU5 as an Auxiliary Component of a Phage Cocktail for Salmonella Biocontrol [PDF]

Applied and Environmental Microbiology, 2014
ABSTRACT Salmonella spp. are among the major food-borne pathogens that cause mild diarrhea to severe bacteremia. The use of bacteriophages to control various food-borne pathogens, including Salmonella , has emerged as a promising alternative to traditional chemotherapy. We isolated the
Minsik, Kim, Sujin, Kim, Bookyung, Park, Sangryeol, Ryu   +3 more
openaire   +2 more sources

A Method for Generation Phage Cocktail with Great Therapeutic Potential

PLoS ONE, 2012
Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application.In this study, an approach, named "Step-by-Step" (SBS), has been established.
Jingmin Gu, Xiaohe Liu, Yue Li, Wenyu Han, Liancheng Lei, Yongjun Yang, Honglei Zhao, Yu Gao, Jun Song, Rong Lu, Changjiang Sun, Xin Feng   +11 more
openaire   +4 more sources

Bacteriophages to Control Campylobacter in Commercially Farmed Broiler Chickens, in Australia

Frontiers in Microbiology, 2020
This study describes the development and use of bacteriophage cocktails to control Campylobacter in broiler chickens, in a commercial setting, in Queensland Australia, following the birds from farm to the processing plant.
Helene N. Chinivasagam, Wiyada Estella, Lance Maddock, David G. Mayer, Caitlin Weyand, Phillippa L. Connerton, Ian F. Connerton   +6 more
doaj   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Phage therapy: a step forward in the treatment of Pseudomonas aeruginosa infections [PDF]

, 2015
Antimicrobial resistance constitutes one of the major worldwide public health concerns. Bacteria are becoming resistant to the vast majority of antibiotics and nowadays, a common infection can be fatal. To revert this situation, the use of phages for the
Azeredo J, Bruynoghe R, CDC, d'Herelle F, d'Hérelle F, d'Hérelle F, Fajardo A, Guttman B, Little J, Rice TB, Rose T, Sulakvelidze A, Wagner VE   +12 more
core   +1 more source

Microbial Safety of Legumes—A Review: Bacterial Contamination, Foodborne Outbreaks, and Traditional and Innovative Mitigation Strategies

Legume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Demand for plant‐based foods, including legumes, is growing as a result of consumer preferences shifting toward food sustainability and plant‐based, protein‐rich foods. However, to ensure the food safety of such alternatives, assessing the prevalence of foodborne pathogens related to these products is critical, especially with their increasing
Natoavina T. Faliarizao, Narindra Randriamiarintsoa, Teresa M. Bergholz, Kirk D. Dolan   +3 more
wiley   +1 more source

Comparative study on the virulence of mycobacteriophages

Journal of Virology
The global tuberculosis (TB) epidemic affected 10 million people and caused 1.3 million deaths in 2022 alone. Multidrug-resistant TB is successfully treated in less than 60% of cases by long, expensive, and aggressive treatments.
Ilaria Rubino, Carlos A. Guerrero-Bustamante, Melissa Harrison, Sheila Co, Isobel Tetreau, Mani Ordoubadi, Sasha E. Larsen, Rhea N. Coler, Reinhard Vehring, Graham F. Hatfull, Dominic Sauvageau   +10 more
doaj   +1 more source

Comparative Genomics of 9 Novel Paenibacillus Larvae Bacteriophages [PDF]

, 2016
American Foulbrood Disease, caused by the bacterium Paenibacillus larvae, is one of the most destructive diseases of the honeybee, Apis mellifera. Our group recently published the sequences of 9 new phages with the ability to infect and lyse P.
Amy, Penny S., LeBlanc, Lucy, Stamereilers, Casey, Tsourkas, Philippos K., Yost, Diane   +4 more
core   +2 more sources

Computational front end to diverse therapeutic phage cocktails

, 2020
New therapies are necessary to combat increasingly antibiotic-resistant bacterial pathogens. We have developed a technology platform of computational, molecular biology, and microbiology tools which together enable on-demand production of phages that ...
Catherine M. Mageeney, Anupama Sinha, Richard Mosesso, D. Medlin, Britney Y. Lau, Alecia B. Rokes, T. Lane, S. Branda, K. Williams   +8 more
semanticscholar   +1 more source