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Virus Research, 2016 The aim of this study was to compare the dynamics of three previously isolated bacteriophages (or phages) individually (phSE-1, phSE-2 and phSE-5) or combined in cocktails of two or three phages (phSE-1/phSE-2, phSE-1/phSE-5, phSE-2/phSE-5 and phSE-1/phSE-2/phSE-5) to control Salmonella enterica serovar Typhimurium (Salmonella Typhimurium) in order to ...
Ivonne Delgadillo +2 more
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Phage Cocktail Therapy: Multiple Ways to Suppress Pathogenicity
Trends in Plant Science, 2020Phage cocktails have emerged as precision tools for controlling plant bacterial diseases. Wang et al. now report that phage cocktails decreased the occurrence of tomato bacterial wilt disease efficiently by infecting and destroying bacterial pathogens, selecting phage-resistant but slow-growing pathogen strains, and fostering bacterial species that are
Na, Liu +3 more
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Efficiency of phage cocktails in the inactivation of Vibrio in aquaculture
Aquaculture, 2014Abstract Aquaculture is one of the fastest growing sectors in the world, having a very important role in the economy. However, the losses associated with bacterial infections such as vibriosis, lead to huge economic costs. The regular use of antibiotics in aquaculture has resulted in the development of resistant strains, which have contributed to the
Adelaide Almeida, Angela Cunha
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New Phage cocktail against infantile Sepsis bacteria
Microbial Pathogenesis, 2020A total of 54 positive blood aerobic cultures of suspected blood sepsis in neonates were purified, diagnosed and tested for antibiotic susceptibility. Six bacterial pathogens of Escherichia coli (10 isolates), Klebsiella pneumoniae (10 isolates), Haemophilus influenzae (4 isolates), Pseudomonas aeruginosa (3 isolates), Citrobacter fruendii (1 isolate ...
Sadeq Abdulridha, Gatea Kaabi +1 more
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A game of resistance: War between bacteria and phages and how phage cocktails can be the solution
VirologyWhile phages hold promise as an antibiotic alternative, they encounter significant challenges in combating bacterial infections, primarily due to the emergence of phage-resistant bacteria. Bacterial defence mechanisms like superinfection exclusion, CRISPR, and restriction-modification systems can hinder phage effectiveness.
Adelaide Almeida +2 more
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Phage therapy pharmacology phage cocktails.
Advances in applied microbiology, 2016Phage therapy is the clinical or veterinary application of bacterial viruses (bacteriophages) as antibacterial "drugs." More generally, phages can be used as biocontrol agents against plant as well as foodborne pathogens. In this chapter, we consider the therapeutic use of phage cocktails, which is the combining of two or more phage types to produce ...
Benjamin K, Chan, Stephen T, Abedon
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Efficacy of two Staphylococcus aureus phage cocktails in cheese production
International Journal of Food Microbiology, 2016Staphylococcus aureus is one of the most prevalent pathogenic bacteria contaminating dairy products. In an effort to reduce food safety risks, virulent phages are investigated as antibacterial agents to control foodborne pathogens. The aim of this study was to compare sets of virulent phages, design phage cocktails, and use them in a cocktail to ...
Claude P Champagne +2 more
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Phage cocktail administration to reduce Salmonella load in broilers
Research in Veterinary ScienceSalmonella is a serious foodborne pathogen that can cause gastrointestinal disease through the consumption of contaminated foods; including poultry meat. Salmonella is commonly present in the intestinal tract of poultry and farm environments, posing a potential risk of contamination during the processing of poultry meat.
Wattana, Pelyuntha +5 more
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Single Phage and Cocktail Therapy
Phage therapy has emerged as a compelling alternative to conventional antibiotics, especially when tackling bacteria that resist multiple drugs. This approach can be split into two key strategies: single phage therapy, where a thoughtfully chosen phage strain takes the lead, and phage cocktail therapy, combining multiple phages to broaden antibacterialopenaire +1 more source
Evaluation of phage cocktails to prevent avian colibacillosis
2022Colibacillosis is the main bacterial disease in poultry and is treated mainly by antibiotics, which eventually led to the emergence of antibiotic resistant strains. Our objective was to evaluate the efficacy of two phage cocktails to prevent colibacillosis induced in chicks by the pathogenic strain BEN4358.
Nicolas, Marianne +7 more
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