Results 81 to 90 of about 64,822 (118)

Synergistic effects of halo-plaque forming phage cocktails against polymicrobial Acinetobacter baumannii and Staphylococcus aureus

Microbiology Spectrum
Antimicrobial resistance is a growing global health crisis, with polymicrobial infections caused by Acinetobacter baumannii and Staphylococcus aureus posing a significant healthcare challenge due to their synergistic virulence, multidrug resistance, high
Ampapan Naknaen, Arrita Rueangrit, Wanna Sudhikaran, Arnon Chukamnerd, Sanicha Chumtong, Sarunyou Chusri, Rattanaruji Pomwised, Komwit Surachat, Kamonnut Singkhamanan, Ruttayaporn Ngasaman   +9 more
doaj   +1 more source

METAGENOMIC STUDY TOWARDS PHAGE THERAPY INPROVEMENT: WHAT DO WE LEARN FROM BALANCE AND BACTERIA / PHAGE RATIO? [PDF]

Phage therapy can be most simply understood as an alternative to antibiotics, especially in the context of bacterial infections that have developed resistance to conventional treatments.
Cristina Giaroni, Gustavo Di Lallo, David Brandtner, Pietro D’Addabbo, Roberto Malinverni, Walter Sanseverino, Giuseppina La Rosa, FREZZA Domenico, Andreina Baj, Annalisa Bosi, Pamela Mancini, Rossella Cianci., Marcello Iaconelli   +12 more
core  

Comparative genomics defines the core genome of the growing N4-like phage genus and identifies N4-like Roseophage specific genes [PDF]

, 2014
Two bacteriophages, RPP1 and RLP1, infecting members of the marine Roseobacter clade were isolated from seawater. Their linear genomes are 74.7 and 74.6 kb and encode 91 and 92 coding DNA sequences, respectively.
Schäfer, Hendrik, Jacqueline Zoe-Munn Chan, Nicholas Harold Mann, Chan, Jacqueline, Andrew David Millard, Millard, Andrew D., Jacqueline Z.-M. Chan, Mann, Nicholas H., Hendrik eSchäfer, Andrew D. Millard, Nicholas H. Mann, Hendrik Schäfer   +11 more
core   +1 more source

Optimizing the Timing and Composition of Therapeutic Phage Cocktails: A Control-Theoretic Approach

, 2019
International audienceViruses that infect bacteria, i.e., bacteriophage or 'phage,' are increasingly considered as treatment options for the control and clearance of bacterial infections, particularly as compassionate use therapy for multi-drug-resistant
Leung, Chung Yin, Weitz, Joshua, S, Wardi, Yorai, Debarbieux, Laurent, Li, Guanlin   +4 more
core   +1 more source

A New Approach for Phage Cocktail Design in the Example of Anti-Mastitis Solution

Pathogens
The studies on phage therapy have shown an overall protective effect of phages in bacterial infections, thus providing an optimistic outlook on the future benefits of phage-based technologies for treating bacterial diseases.
Daria Królikowska, Marta Szymańska, Marta Krzyżaniak, Arkadiusz Guziński, Rafał Matusiak, Agnieszka Kajdanek, Edyta Kaczorek-Łukowska, Agnieszka Maszewska, Ewelina A. Wójcik, Jarosław Dastych   +9 more
doaj   +1 more source

Ackermannviridae bacteriophage against carbapenem-resistant Klebsiella pneumoniae of capsular type 64

Frontiers in Microbiology
Lytic bacteriophages (phages) are promising clinically viable therapeutic options against carbapenem-resistant Klebsiella pneumoniae (CRKP). In China, the predominant strains are those assigned to sequence type 11 and capsular type 64 (ST11-KL64).
Juan Li, Juan Li, Yu Feng, Huan Luo, Qingqing Fang, Qingqing Fang, Yongqiang Yang, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong, Zhiyong Zong   +10 more
doaj   +1 more source

FORMULATING PHAGE COCKTAILS AS ADJUVANT THERAPY IN CARBAPENEM-RESISTANT PSEUDOMONAS AERUGINOSA

Open Respiratory Archives
Introduction: Phage-antibiotic synergy (PAS) results in bacterial killing beyond the efficacy of either agent alone. Although the main candidates for therapeutic PAS are lytic phages, temperate phages have been re-evaluated in light of PAS.
Viviane de Cássia Oliveira, Amanda Carolina Souza Delfino da Rocha, Alba Soler-Comas, Guillen Macip, Miguel Ferrer, Antoni Torres, Laia Fernandez-Barat   +6 more
doaj   +1 more source

Phage Therapy at the Crossroads Between Clinical Promise and Regulatory Challenge

Pharmaceuticals
Bacteriophage (phage) therapy, including monophage preparations, phage cocktails, engineered phages, and phage-derived enzymes, has re-emerged as a potential option for difficult-to-treat and biofilm-associated infections in the context of rising ...
Anna Gallina, Matteo Gallina, Andrea Cona, Patrizio Vitulo, Alessandra Mularoni, Alessio Provenzani   +5 more
doaj   +1 more source

Orf protein modulates phage and bacterial pathways of genetic recombination [PDF]

, 2008
The emergence of novel pathogenic organisms due to the acquisition of virulencedeterminants from bacteriophages has generated significant interest in the pathways responsible for genomic rearrangements.
Bowers, Laura Yvonne
core  

Inactivation of Salmonella Enteritidis in liquid egg yolk and egg white using bacteriophage cocktails

Current Research in Food Science
Salmonella Enteritidis (SE) is a significant global cause of foodborne illness, often linked to egg contamination. This study evaluated the inhibitory effects of eight bacteriophages (phages) against three SE strains isolated from poultry environments ...
Jiangning He, Catherine W.Y. Wong, Danielle M. Schultze, Siyun Wang   +3 more
doaj   +1 more source