Results 121 to 130 of about 978,488 (287)
Advanced Science, EarlyView.Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang +4 more
wiley +1 more source
Site‐Specific Protein Bioconjugation Through Cellular Incorporation of Noncanonical Amino Acids
Angewandte Chemie, EarlyView.Genetic code expansion (GCE) enables site‐specific installation of noncanonical amino acids containing bioorthogonal conjugation handles, allowing precise, homogeneous protein modification. This review examines the principles of orthogonal translation, surveys the chemistries available for chemoselective labeling, and highlights emerging multi‐site ...
Rahul Sarkar +2 more
wiley +2 more sources
Interactive Auditory Display of Urban Spatio-Acoustics
, 2014 Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.Presented at the 20th International Conference on Auditory Display (ICAD2014), June 22-25, 2014, New York, NY.This paper presents an interactive
Turner, Johnathan +2 more
core +1 more source
Advanced Science, EarlyView.Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim +5 more
wiley +1 more source
Music monitor: Dynamic data display
, 2000 Presented of the 6th International Conference on Auditory Display (ICAD), Atlanta, GA, April 2-5, 2000Presented at the 6th International Conference on Auditory Display (ICAD), Atlanta, GA, April 2-5, 2014In this demo, we present an interface prototype of
Mynatt, Elizabeth D., Tran, Quan T
core +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Effective Depletion of Albumin Using a Novel M13 Phage Display Library Based Technique
, 2008 Effective Depletion of Albumin Using a Novel M13 Phage Display Library Based ...
梁振, 张玉奎, 赵鹏, 张丽华
core
Advanced Science, EarlyView.(A) Establishment and characterization of the osteosarcoma‐targeted dual‐delivery nanoplatform mBAP1/siENO1@LNP‐OTP for simultaneous regulation of BAP1 and ENO1 in tumor cells. (B) After intravenous administration, mBAP1/siENO1@LNP‐OTP preferentially accumulates at tumor sites through OTP‐mediated targeting.
Yechao Shen +13 more
wiley +1 more source
Angewandte Chemie, EarlyView.DNA structures with short single‐strand gaps in the non‐template strand of the T7 promoter prevent transcription by T7 RNA polymerase. Contrary to intuition, however, transcriptional activity can be observed again when the size of the gap increases toward the transcription start site, thereby reducing the proportion of double‐stranded DNA in the ...
Michael W. Haydell +2 more
wiley +2 more sources
Quantifying Structure‐Dependent Rigidity of 3D DNA Origami Boxes
Advanced Intelligent Systems, EarlyView.We investigate the mechanical stability of a hollow 3D DNA origami box during assembly using liquid AFM imaging and finite element simulations. As structural completeness increases from flat sheets through intermediate assemblies to a closed box, rigidity improves.
Judith Zubia‐Aranburu +5 more
wiley +1 more source