Results 171 to 180 of about 63,473 (252)

DOM: Dual Optical Mapping Integrating Sequence‐Specific Barcodes and A/T Density Profiles

Small Methods, EarlyView.
Dual Optical Mapping (DOM) combines sequence‐specific barcodes and an A/T profile to generate complementary genomic signatures along single DNA molecules. The integration of sparse and dense mapping information enables accurate and confident genome mapping, facilitating reliable localization of long DNA molecules in complex genomes, including the ...
Jaeyoung Bae, Yunchul Kim, Joohee Choe, Jinhui Hong, Byoungsang Lee, Kaori Hashiya, Toshikazu Bando, Hiroshi Sugiyama, Seonghyun Lee, Jung Heon Lee, Kyubong Jo   +10 more
wiley   +1 more source

Generation Using Phage-Display of pH-Dependent Antibodies Against the Tumor-Associated Antigen AXL. [PDF]

Antibodies (Basel)
Mangeat T, Mairaville C, Chentouf M, Neiveyans M, Pugnière M, Ngo G, Denis V, Catherine C, Pichard A, Deshayes E, Maurel M, Gracia M, Bigot A, Mouly V, Estaran S, Chavanieu A, Martineau P, Robert B.   +17 more
europepmc   +1 more source

Diagnostic antibodies at an inflection point: From discovery platforms to design‐oriented engineering

VIEW, EarlyView.
This study systematically organizes the evolution of diagnostic antibodies from discovery platforms to design‐oriented engineering and analyzes the strengths and limitations of each approach. Meanwhile, it provides a critical, literature‐driven synthesis of current challenges, proposing integrated strategies for assay‐aware and function‐driven antibody
Qitao Song, Lulai Xu, Weilin Wu, Fei Xie, Yantong Pan, Tiantian Yang, Xiaoxia Xu, Yanyin Lin, Lihua Zhang, Jiahui Zhou, Junyou Zhou, Linping Li, Zhanhui Wang, Weijing Yi, Jing Wang   +14 more
wiley   +1 more source

Pioneer: a synthetic human antibody phage display library for rapid therapeutic lead generation. [PDF]

MAbs
Putyrski M, Hentrich C, Cavada M, Wich M, Kellmann SJ, Hanselka S, Eick-Werner M, Hanuschka H, Preis W, Werkmeister C, Klee M, Knappik A, Ylera F.   +12 more
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Immune Imprinting Identified in Phage-Display Antibody Libraries Derived from Early Wild-Type and Late Omicron COVID-19 Convalescents. [PDF]

Viruses
Li B, Wang M, Huang F, Wu W, Fan J, Yang L, Pan Y, Liang M, Duan K.   +8 more
europepmc   +1 more source

Wastewater treatment plant as a stable contributor affecting coastal ocean water viral communities

mLife, EarlyView.
Qiji Zhang, Zhanwen Cheng, Xiaotong Tang, Yuxi Yan, Yu Xia   +4 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Mycobacterium intracellulare M.i.198—A Promising Strain for Studying Pathogenesis of Nontuberculous Mycobacterial Pulmonary Disease (NTM‐PD)

Microbiology and Immunology, EarlyView.
ABSTRACT In this review, we introduce a promising strain for studying pathogenesis of nontuberculous mycobacterial pulmonary disease (NTM‐PD), Mycobacterium intracellulare M.i.198. M.i.198 was isolated from a patient with progressive Mycobacterium avium‐intracellulare complex pulmonary disease (MAC‐PD) in whom surgical operation was required to ...
Yoshitaka Tateishi, Ryoji Maekura, Yukiko Nishiuchi, Sohkichi Matsumoto   +3 more
wiley   +1 more source