Results 181 to 190 of about 978,488 (287)

DNA Nanotechnology Meets Peptide and Protein Self‐Assembly

Chemistry – A European Journal, EarlyView.
Combining DNA nanotechnology with peptide and protein assembly provides complementary platforms for the rational engineering of functional biomaterials. This Perspective discusses the emerging field of self‐assembling DNA‐peptide and DNA‐protein hybrid systems that combine the structural precision and programmability of DNA nanotechnology with the ...
Marcel Hanke, Nanjundan Raghul, Adrian Keller, Veikko Linko, Verónica I. Dodero   +4 more
wiley   +1 more source

From Phage Display to Yeast Secretion: Developing Fc-Fused Nanobodies Against Influenza Virus. [PDF]

Cells
Wang M, Li S, Li Y, Xia X, Zhang Y, Cao N, Li Y, Liu Y, Zhang S, Zhang L, Huang J.   +10 more
europepmc   +1 more source

Microbiome and Tumor Microenvironment Interactions: Advances From Ecological Niches to Precision Oncology

Cancer Nexus, EarlyView.
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang, Ji'an Liu, Jing Li, Xue Liu, Yang Su, Peng Luo, Yuhan Zhang, Zhengrui Li   +7 more
wiley   +1 more source

Phage Display Selection and In Silico Characterization of Peptides as Potential GroEL Modulators. [PDF]

Pharmaceutics
Olla S, Colombarolli SG, Siguri C, Murrau D, Vitali A.   +4 more
europepmc   +1 more source

Single‐Cell Reporter Dynamics During the First Two Rounds of Rhinovirus Plaque Growth

Cytometry Part A, EarlyView.
ABSTRACT When infection spreads from an initially infected cell through a cell monolayer, the resulting plaque records successive rounds of virus–cell interaction. Fluorescent reporter viruses permit this process to be followed at single‐cell resolution, but whether secondary infected cells retain detectable signatures associated with their plaque of ...
Rahul Ramachandran, Huicheng Shi, John Yin   +2 more
wiley   +1 more source

Serum-antibody Profiling of H3N2-infected Ferrets Using a Combinatorial Phage-display Random Peptide Library. [PDF]

J Mol Biol
Yehudai T, Tamazian G, Uppalapati L, Völs S, Sridhar S, Cortés G, Vogel TU, Roitburd-Berman A, Gershoni JM.   +8 more
europepmc   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

The first thermophilic phage display system. [PDF]

Mater Today Bio
Skowron PM, Sobolewski I, Adamowicz K, Morcinek-Orłowska J, Gaffke L, Jaroszewicz W, Łubkowska B, Pierzynowska K, Zylicz-Stachula A, Węgrzyn G.   +9 more
europepmc   +1 more source

A PD‐L1 Nanobody‐Engineered Synthetic RNA Virus Enhances Hepatocellular Carcinoma Immunotherapy by Interfering PCSK9 and Upregulating MHC‐I

Exploration, EarlyView.
A PD‐L1 nanobody‐engineered synthetic RNA virus (αPDL1‐VLPs/shPCSK9) is fabricated to inhibit PCSK9 and upregulate MHC‐I to facilitate T cells recognition of hepatocellular carcinoma (HCC). Moreover, αPDL1‐VLPs/shPCSK9 can recognize PD‐L1 and block the PD‐1/PD‐L1 pathway to prevent immune evasion, while promoting M2‐to‐M1 macrophages polarization ...
Chuyu Huang, Yun Ye, Yi Guo, Guozheng Liao, Linyi Luo, Lingwen Ding, Yingling Miao, Linping Zhao, Yongchang Ouyang, Shiying Li   +9 more
wiley   +1 more source

Integrated metagenomic sequencing and phage display-based immunoprecipitation sequencing for presumptive viral infection: a case report. [PDF]

Am J Ophthalmol Case Rep
Shantha JG, Chen C, Hinterwirth A, Gonzales JA, Acharya NR, Lietman TM, Doan T.   +6 more
europepmc   +1 more source