Results 181 to 190 of about 63,473 (252)

High-Throughput Identification and Characterization of LptDE-Binding Bicycle Peptides Using Phage Display and Cryo-EM. [PDF]

J Med Chem
Allyjaun S, Dunbar E, Hardwick SW, Newell S, Holding F, Rowland CE, St Denis MA, Pellegrino S, Arruda Bezerra G, Bournakas N, Chirgadze DY, Cooper L, Paris G, Lewis N, Brown P, Skynner MJ, Dawson MJ, Beswick P, Hubbard J, van den Berg B, Newman H.   +20 more
europepmc   +1 more source

Genome Analysis of Corynebacterium ulcerans Isolates Chronologically Recovered From the Same Cat for Two Years: Circulation in a Cat Shelter

Microbiology and Immunology, EarlyView.
ABSTRACT Toxigenic Corynebacterium ulcerans, a zoonotic pathogen, was isolated repeatedly from a cat in an in‐house group in Japan. Although the cat was cured once by antibiotic treatment, clonal isolates of the original pathogenic strain were recovered repeatedly during a 2‐year course.
Ryoko Jikihara, Miyuki Kimura, Hyun Kim, Tsuyoshi Sekizuka, Masatomo Morita, Makoto Kuroda, Akihiko Yamamoto, Mitsutoshi Senoh, Masaaki Iwaki   +8 more
wiley   +1 more source

Defining short linear motif binding determinants by phage display-based deep mutational scanning. [PDF]

Protein Sci
Benz C, Maassen L, Simonetti L, Mihalic F, Lindqvist R, Tsitsa I, Konstantinou A, Jemth P, Överby AK, Davey NE, Ivarsson Y.   +10 more
europepmc   +1 more source

Hotter, faster, sicker? Warming shifts the cost of infection from individuals to populations

Journal of Animal Ecology, EarlyView.
This study examines how temperature alters disease impacts across biological scales in a host–pathogen system. We found infected hosts appear healthiest at warm temperatures, yet populations suffer most. This suggests climate warming may intensify disease impacts for populations in ways traditional individual‐level virulence metrics fail to predict ...
Nathan J. Butterworth, Kerri J. Moore, Matthew D. Hall   +2 more
wiley   +1 more source

Identification of novel human IgE-binding peptides from a phage display library for total IgE detection. [PDF]

Sci Rep
Kaew-Amdee S, Makornwattana M, Charlermroj R.   +2 more
europepmc   +1 more source

Mapping Allergen B‐ and T‐Cell Epitopes: Technological Advances and Their Role in Precision Allergy Therapy

Allergy, EarlyView.
ABSTRACT Allergic diseases arise from aberrant immune recognition of otherwise harmless environmental proteins and are driven by epitope‐specific interactions between allergens and the adaptive immune system. Although component‐resolved diagnostics have improved molecular characterisation of sensitization, they remain limited to whole‐allergen ...
Mark Møiniche, Josefine Corneliussen, Kristoffer H. Johansen, Alexandre Ruiz‐Carrasco, Caroline Paulsen, Yuchen Li, Carolina Barra, Sandhya Bangaru, Monica L. Fernández‐Quintero, Ewa Bartko, Lars Blom, Esperanza Rivera‐de‐Torre   +11 more
wiley   +1 more source

Discovery of d‑Miniprotein Inhibitors of PD-1/PD-L1 Interaction via Mirror-Image Phage Display against Synthetic d‑PD‑1. [PDF]

JACS Au
Zhou H, Wu H, Zhong Z, Blasco P, Zeng J, Wang J, Liu H, Li X.   +7 more
europepmc   +1 more source

Diet–Microbiome–Immune Interactions at the Gut Mucosa in Food Allergy: Mechanisms, Gaps, and Therapeutic Implications

Allergy, EarlyView.
ABSTRACT Mucosal surfaces are sites of highly dynamic interactions among epithelial and immune cells, environmental exposures, particularly dietary inputs, and the diverse microbial communities and their metabolites. These elements continually influence each other to maintain homeostasis and ensure appropriate immune discrimination between pathogens ...
Clara Delaroque, Liam O'Mahony, Inge Kortekaas Krohn, Charlotte G. Mortz, Markus Ollert, Mahesh S. Desai   +5 more
wiley   +1 more source

Optimization of a sarbecovirus llama nanobody-antigen binding interface via a combined computational and phage display protein engineering approach. [PDF]

Proc Natl Acad Sci U S A
Ramos KE, Nandigrami P, Najafian A, Lai JR, Fiser A.   +4 more
europepmc   +1 more source