Results 231 to 240 of about 113,145 (298)

Insights into the catalytic mechanism of formate dehydrogenases from different microbial sources

open access: yesThe FEBS Journal, EarlyView.
This integrated study combines experimental enzyme kinetics with QM/MM simulations to map the catalytic mechanisms of four formate dehydrogenases at the atomic level. This approach reveals the key determinants of catalytic efficiency and guides the rational design of biocatalysts for effective CO2 reduction—a crucial step towards sustainable ...
Laura Legnani   +8 more
wiley   +1 more source

Discovery of Antibodies Against Endemic Coronaviruses with NGS-Based Human Fab Phage Display Platform. [PDF]

open access: yesAntibodies (Basel)
Pan OC   +16 more
europepmc   +1 more source

Microbiome of Apical Intracanal and Extraradicular Biofilms From the Same Roots of Teeth With Persistent Apical Periodontitis: An Observational Study

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi   +11 more
wiley   +1 more source

Potential of the Predatory Mites Gamasellodes lavafesii (Mesostigmata: Ascidae) and Cosmolaelaps mediocuspis (Mesostigmata: Laelapidae) on Different Soil Pests/Parasites and Alternative Prey for Large‐Scale Rearing

open access: yesJournal of Applied Entomology, EarlyView.
ABSTRACT Many species of Mesostigmata soil mites have potential as biological control agents of pests/parasites. This study evaluated the predation potential of two of these species, Gamasellodes lavafesii (Ascidae) and Cosmolaelaps mediocuspis (Laelapidae).
A. R. A. Barros   +4 more
wiley   +1 more source

Identification of Covalent Cyclic Peptide Inhibitors Targeting Protein-Protein Interactions Using Phage Display. [PDF]

open access: yesJ Am Chem Soc
Wang S   +12 more
europepmc   +1 more source

Phage Therapy: Targeting the Gut Microbiota for the Treatment of Acute Pancreatitis

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Acute pancreatitis (AP) is a common clinical inflammatory condition whose severity is closely associated with both local pancreatic injury and systemic complications. Research indicates that gut microbiota dysbiosis and subsequent bacterial translocation can exacerbate disease progression via the gut–pancreas axis, representing a critical ...
Jiawei Chen   +4 more
wiley   +1 more source

AI-enhanced profiling of phage-display-identified anti-TIM3 and anti-TIGIT novel antibodies. [PDF]

open access: yesFront Immunol
Musnier A   +11 more
europepmc   +1 more source

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