Results 201 to 210 of about 4,514,314 (397)

Chemical Composition and Synergistic Antimicrobial Effects of Essential Oils From Four Commonly Used Satureja Species in Combination With Two Conventional Antibiotics

open access: yesChemistry &Biodiversity, EarlyView.
The chemical composition and the in vitro synergistic antimicrobial effects of four Satureja essential oils were investigated. Essential oils from Satureja montana and S. hortensis displayed strong antimicrobial effects, whereas S. calamintha and S. alpina exhibited relatively weaker antimicrobial activity.
Imane Abbad   +3 more
wiley   +1 more source

Self-assembling T7 phage syringes with modular genomes for targeted delivery of penicillin against beta-lactam-resistant Escherichia coli [PDF]

open access: yesarXiv
Bacteriophages are promising alternative antimicrobial agents due to their high specificity for host bacteria and minimal immunogenicity in humans. However, their therapeutic application is limited by their nature as biological entities, which can lead to unintended evolutionary consequences such as horizontal gene transfer.
arxiv  

Promising Prodiginins Biological Activities

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Prodiginins are a large family of at least 34 pyrrolic compounds, including the well‐studied red pigment prodigiosin. Prodiginins are produced by several microorganisms displaying broad biological activities, including antimicrobial, antiviral, antiparasitic, antiproliferative, and immunosuppressive activities.
María F. Ladetto   +6 more
wiley   +1 more source

Mechanisms of Multi-strain Coexistence in Host-Phage Systems with Nested Infection Networks [PDF]

open access: yesarXiv, 2013
Bacteria and their viruses ("bacteriophages") coexist in natural environments forming complex infection networks. Recent empirical findings suggest that phage-bacteria infection networks often possess a nested structure such that there is a hierarchical relationship among who can infect whom.
arxiv  

Review on Phage Therapy

open access: yes, 2022
Phage Therapy, which uses bacteriophages to combat a bacterial infection, has been around since the 1920s but was overshadowed by the success of antibiotics. The rise in antibiotic resistance has regenerated curiosity into the potential of this practice.
openaire   +1 more source

Engineering and Structural Elucidation of a Sac7d‐Derived IgG Fc‐Specific Affitin and Its Application for the Light‐Controlled Affinity Purification of Antibodies

open access: yesChemBioChem, EarlyView.
An affitin derived from the Sac7d scaffold enables the light‐controlled affinity purification of antibodies under physiological conditions, thus overcoming limitations of protein A chromatography. X‐ray crystallographic analysis and affinity measurements reveal complex formation with Fc at the CH2/CH3 junction, similar to protein A/G and FnRn. Combined
Felix Veitl   +7 more
wiley   +1 more source

Selective [9‐15N] Guanosine for Nuclear Magnetic Resonance Studies of Large Ribonucleic Acids

open access: yesChemBioChem, EarlyView.
The small chemical shift anisotropy of nitrogen‐15 at the 9‐position in guanine (15N9‐G) leads to long T2 values and narrow NMR lines, particularly attractive to probe structure and dynamics of large (>200 nucleotide) ribonucleic acids (RNAs). RNAs regulate various cellular processes using malleable 3D structures, and understanding the factors that ...
Solomon K. Attionu   +5 more
wiley   +1 more source

DepoRanker: A Web Tool to predict Klebsiella Depolymerases using Machine Learning [PDF]

open access: yesarXiv
Background: Phage therapy shows promise for treating antibiotic-resistant Klebsiella infections. Identifying phage depolymerases that target Klebsiella capsular polysaccharides is crucial, as these capsules contribute to biofilm formation and virulence. However, homology-based searches have limitations in novel depolymerase discovery.
arxiv  

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