Results 201 to 210 of about 114,190 (344)

Characterization of Non‐Specific Electrostatic Interactions of Cationic Peptides with DNA Origami and Their Functional Consequences

Small Methods, EarlyView.
DNA origami offers a precise platform for peptide functionalization, but its negatively charged scaffold causes severe non‐specific adsorption of cationic peptides. This study systematically quantifies this electrostatic artifact and introduces a charge‐tailored polyethylene glycol (PEG) purification workflow that restores stoichiometric control.
Seung Hyun Kang, Oheun Kwon, Bo Kyung Cho, Seungmin Yoo, Jin Myeong Wang, Youngjin Choi, Hong Yeol Yoon, Jungkyu Choi, Ju Hee Ryu   +8 more
wiley   +1 more source

Regulation of phage therapy medicinal products: developments, challenges, and opportunities. [PDF]

Front Cell Infect Microbiol
Fuerst-Wilmes M, Respondek V, Schramm M, Lilienthal N, Buss K, Duechting A.   +5 more
europepmc   +1 more source

Cas12Fold Accurately Predicts Cas12 Nuclease Structures to Enable Structure‐based Genome‐editing Engineering

Small Structures, EarlyView.
Cas12Fold, a deep‐learning framework tailored to Cas12 nucleases, uses evolutionary signals and iterative structure‐based alignment to resolve conformational complexity. This method outperforms general models in predicting key domains and states, accurately modeling enzymes such as Casλ.
Feng Xu, Zilong Zhao, Chang Liu, Meixia Yu, Ke Li, Yilin Jing, Peiyang Li, Beibei Xin, Jian Chen, Lizhu E, Jinsheng Lai, Zhijia Yang, Hainan Zhao   +12 more
wiley   +1 more source

Phage Therapy as a New Approach in Treating Emerging Antibiotic Resistant Infections

, 2018
Ramak Ajideh, Mohammad Ali Faramarzi, Mohammad Hossein Yazdi, Mohammad Reza Pourmand   +3 more
openalex   +2 more sources

PGN_0298 in the Assembly and Insertion Machinery (Aim) Operon Is Essential for the Viability of Porphyromonas gingivalis

Microbiology and Immunology, EarlyView.
ABSTRACT Porphyromonas gingivalis is a typical periodontal pathogen, and one of its key virulence factors is the powerful protease gingipains. Gingipains are secreted via the type IX secretion system (T9SS) and are associated with the assembly and insertion machinery (Aim) operon (PGN_0296 to PGN_0301), which encodes both T9SS components and non‐T9SS ...
Shintaro Ono, Katsuki Takebe, Ikue Tosa, Yuki Nishiya, Masaaki Nakayama, Takayuki Wada, Shogo Takashiba, Naoya Ohara   +7 more
wiley   +1 more source

Phage therapy as a revitalized weapon for treating clinical diseases. [PDF]

Microbiome Res Rep
Wang Y, Yu Y.
europepmc   +1 more source

Phage therapy

Journal of Pharmacy and Pharmacology, 1998
openaire   +1 more source

Phage therapy for intestinal infections: efficacy, challenges, and future directions in translational research. [PDF]

Front Microbiol
Wang X, Li J, Ge Z, Fan J, Ma D, Cao H, Shen J, Wang Y, Liu Z, Gomaa SE, Li X, Ji X, Teng T.   +12 more
europepmc   +1 more source

B‐Cell Repertoire of Children With Atopic Dermatitis Exhibits Altered IgE Maturation Associated With Allergic Food Sensitization

Allergy, EarlyView.
IgH repertoire sequencing of a large atopic dermatitis cohort reveal reduced IgE somatic hypermutation and increased IgE diversity associated with food allergen sensitization. Presence of a dog during the first year of life is associated with increased IgE somatic hypermutation, possibly countering the effect of food sensitization.
Kirandeep K. Gill, Carolina Moore, Onyekachi Nwogu, John W. Kroner, Wan‐Chi Chang, Jeffrey Burkle, Samuel J. Virolainen, Mariana L. Stevens, Asel Baatyrbek, Emily R. Miraldi, Jocelyn M. Biagini, Ashley L. Devonshire, Leah Kottyan, Justin T. Schwartz, Amal H. Assa'ad, Lisa J. Martin, Sandra Andorf, Gurjit K. Khurana Hershey, Krishna M. Roskin   +18 more
wiley   +1 more source

Phage Therapy as a Novel Alternative to Antibiotics Through Adaptive Evolution and Fitness Trade-Offs. [PDF]

Antibiotics (Basel)
Zhang S, Ahn J.
europepmc   +1 more source