Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions.
Journal of Clinical Investigation, 2019 Resolution of acute inflammation is an active process orchestrated by endogenous mediators and mechanisms pivotal in host defense and homeostasis.
Chia Nan +4 more
semanticscholar +1 more source
Fungal Symbionts Produce Prostaglandin E2 to Promote Their Intestinal Colonization
Frontiers in Cellular and Infection Microbiology, 2019 Candida albicans is a ubiquitous fungal symbiont that resides on diverse human barrier surfaces. Both mammalian and fungal cells can convert arachidonic acid into the lipid mediator, prostaglandin E2 (PGE2), but the physiological significance of fungus ...
Tze Guan Tan +4 more
doaj +1 more source
Brain Abscess as Severe Presentation of Specific Granule Deficiency
Frontiers in Pediatrics, 2020 Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule ...
Maria Leszcynska +9 more
doaj +1 more source
Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages
Frontiers in Immunology, 2021 Phagocytosis is an essential process for the uptake of large (>0.5 µm) particulate matter including microbes and dying cells. Specialized cells in the body perform phagocytosis which is enabled by cell surface receptors that recognize and bind target ...
Yan Lin Fu +3 more
doaj +1 more source
LC3-Associated Phagocytosis in Bacterial Infection
Pathogens, 2022 LC3-associated phagocytosis (LAP) is a noncanonical autophagy process reported in recent years and is one of the effective mechanisms of host defense against bacterial infection. During LAP, bacteria are recognized by pattern recognition receptors (PRRs),
Jin Yuan +4 more
doaj +1 more source
Macrophage Migration Is Impaired within Candida albicans Biofilms [PDF]
, 2017 Acknowledgments: We thank the Microscopy and Histology Core Facility at the University of Aberdeen. This work was funded by NHS Grampian Endowments (grant RG10191); the Wellcome Trust Strategic Award in Medical Mycology and Fungal Immunology (grant ...
Alonso, Maria F. +3 more
core +2 more sources
Frontiers in Microbiology, 2020 Staphylococcus aureus is a common cause of chronic and relapsing infection, especially when the ability of the immune system to sterilize a focus of infection is compromised (e.g., because of a foreign body or in the cystic fibrosis lung).
Simon M. Stoneham +5 more
doaj +1 more source
The trans-sialidase from Trypanosoma cruzi induces thrombocytopenia during acute Chagas' disease by reducing the platelet sialic acid contents [PDF]
, 2005 Strong thrombocytopenia is observed during acute infection with Trypanosoma cruzi, the parasitic protozoan agent of American trypanosomiasis or Chagas' disease.
Campetella, O. +4 more
core +2 more sources
Rediscovery of mononuclear phagocyte system blockade for nanoparticle drug delivery
Nature CommunicationsRapid uptake of nanoparticles by mononuclear phagocyte system (MPS) significantly hampers their therapeutic efficacy. Temporal MPS blockade is one of the few ways to overcome this barrier – the approach rediscovered many times under different names but ...
I. Zelepukin +2 more
semanticscholar +1 more source
Gastropod-derived haemocyte extracellular traps entrap metastrongyloid larval stages of Angiostrongylus vasorum, Aelurostrongylus abstrusus and Troglostrongylus brevior [PDF]
, 2017 Background: Phagocyte-derived extracellular traps (ETs) were recently demonstrated mainly in vertebrate hosts as an important effector mechanism against invading parasites.
Gärtner, Ulrich +7 more
core +4 more sources