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On phagocytes and macular degeneration [PDF]

open access: yesProgress in Retinal and Eye Research, 2017
Age related macular degeneration (AMD) is a complex multifactorial disease caused by the interplay of age and genetic and environmental risk factors. A common feature observed in early and both forms of late AMD is the breakdown of the physiologically immunosuppressive subretinal environment and the protracted accumulation of mononuclear phagocytes (MP)
X. Guillonneau   +5 more
semanticscholar   +7 more sources

Scrambled Eggs: Apoptotic cell clearance by non-professional phagocytes in the Drosophila ovary [PDF]

open access: yesFrontiers in Immunology, 2017
This manuscript was supported by NIH grant R01 GM060574 to KM.
McCall, Kimberly, Serizier, Sandy B.
core   +2 more sources

THE ORIGIN AND KINETICS OF MONONUCLEAR PHAGOCYTES [PDF]

open access: bronzeJournal of Experimental Medicine, 1968
The origin and turnover of efferent populations of mouse mononuclear phagocytes has been described. Mononuclear phagocytes were defined as mononuclear cells which are able to adhere to glass and phagocytize.
R. van Furth, Zanvil A. Cohn
openalex   +2 more sources

Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes—Activation and Age-Related Effects

open access: yesFrontiers in Immunology, 2018
In the central nervous system (CNS), microglia are innate immune mononuclear phagocytes (CNS MPs) that can phagocytose infectious particles, apoptotic cells, neurons, and pathological protein aggregates, such as Aβ in Alzheimer’s disease (AD).
C Da Via   +2 more
exaly   +2 more sources

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells [PDF]

open access: yesFrontiers in Immunology, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Claudia Cristina Motran   +15 more
doaj   +3 more sources

Integrated single-cell analysis-based classification of vascular mononuclear phagocytes in mouse and human atherosclerosis

open access: yesCardiovascular Research, 2022
Aims Accumulation of mononuclear phagocytes [monocytes, macrophages, and dendritic cells (DCs)] in the vessel wall is a hallmark of atherosclerosis. Using integrated single-cell analysis of mouse and human atherosclerosis, we here aimed to refine the ...
A. Zernecke   +6 more
semanticscholar   +1 more source

TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination

open access: yesJournal of Experimental Medicine, 2021
Remyelination requires the clearance of cholesterol-rich myelin debris within demyelinating lesions by phagocytes. Gouna et al. found that TREM2-dependent formation of lipid droplets is necessary to buffer excess lipids released by myelin injury and ...
Garyfallia Gouna   +7 more
semanticscholar   +1 more source

Promising Anti-Biofilm Agents and Phagocytes Enhancers for the Treatment of Candida albicans Biofilm–Associated Infections

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Little is known about the interactions among phagocytes and antifungal agents and the antifungal immunomodulatory activities on Candida species biofilms. Here, inhibition of C. albicans biofilms and the interactions among biofilms and phagocytes alone or
Yasmine H. Tartor   +6 more
doaj   +1 more source

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