Results 101 to 110 of about 86,040 (309)

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Functional characterisation of phagocytes in the Pacific oyster Crassostrea gigas [PDF]

, 2016
Invertebrates lack canonical adaptive immunity and mainly rely on innate immune system to fight against pathogens. The phagocytes, which could engulf and kill microbial pathogens, are likely to be of great importance and have to undertake significant ...
Shuai Jiang, Tao Zhang, Limei Qiu, Jinsheng Sun, Zhihao Jia, Linsheng Song, Lingling Wang   +6 more
core   +2 more sources

Helminth Infections: Recognition and Modulation of the Immune Response by Innate Immune Cells

Frontiers in Immunology, 2018
The survival of helminths in the host over long periods of time is the result of a process of adaptation or dynamic co-evolution between the host and the parasite. However, infection with helminth parasites causes damage to the host tissues producing the
Claudia Cristina Motran, Claudia Cristina Motran, Leonardo Silvane, Leonardo Silvane, Laura Silvina Chiapello, Laura Silvina Chiapello, Martin Gustavo Theumer, Martin Gustavo Theumer, Laura Fernanda Ambrosio, Laura Fernanda Ambrosio, Ximena Volpini, Ximena Volpini, Daiana Pamela Celias, Daiana Pamela Celias, Laura Cervi, Laura Cervi   +15 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses

Frontiers in Immunology, 2019
Antiviral activities of antibodies may either be dependent only on interactions between the antibody and cognate antigen, as in binding and neutralization of an infectious virion, or instead may require interactions between antibody–antigen immune ...
Matthew Zirui Tay, Kevin Wiehe, Justin Pollara, Justin Pollara   +3 more
doaj   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Significance Changes in Phagocytes Chemotoxine in Pregnant Women [PDF]

, 2010
Pregnant Women have an increased risk for some infections, particularly during the last trimester. Phagocyte emigration from the circulation into tissues is an important aspect of the initial immune response.
Mohammed K. AL-Araji
core   +2 more sources

Effect of melatonin on the oxidative metabolism of colostrum phagocytes of diabetic women [PDF]

, 2011
Aim: the aim of this study was verified the ability of melatonin hormone to modulate the oxidative metabolism of colostral phagocytes from diabetic mothers. Methods: based on 100g-OGTT and glucose profile analysis subjects were allocated into two groups:
Volpato, R., Hara, C., Rudge, Marilza Vieira Cunha, Morceli, G., Honorio-Franca, A., Calderon, Iracema de Mattos Paranhos, Franca, E.   +6 more
core   +2 more sources

Editorial: The Function of Phagocytes in Non-Mammals

Frontiers in Immunology, 2020
Xin-Jiang Lu, Xin-Jiang Lu, Xin-Jiang Lu, Xin-Jiang Lu, Qing Deng, Kim Dawn Thompson   +5 more
doaj   +1 more source

Cigarette Smoke‐Induced Alveolar Macrophage Senescence via GEM/SIRT3‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang, Meidan Wei, Xiangrong Song, Jiaxin Zhang, Lisha Zhang, Sixian Chen, Yaoyu Hu, Hui Gao, Jianxiang Li   +8 more
wiley   +1 more source