Results 111 to 120 of about 86,040 (309)

Melatonin Action on the Activity of Phagocytes from the Colostrum of Obese Women

Medicina, 2019
Background and objectives: Breastfeeding promotion is an important public health strategy for counter-balancing the negative effects of maternal overweight and obesity.
Tassiane C. Morais, Adenilda C. Honorio-França, Mahmi Fujimori, Ocilma B. de Quental, Rafael S. Pessoa, Eduardo L. França, Luiz C. de Abreu   +6 more
doaj   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Immunomodulatory effects of herbal plants plus melatonin on human blood phagocytes [PDF]

, 2011
It has been shown a mixture of seven herbal plants was able to trigger cell oxidative mechanism and subsequently inducing cellular activation. Moreover, melatonin hormone has also been shown to perform different actions on the cellular oxidative ...
Batalini, Claudemir; Federal University of Mato Grosso Pontal do Araguaia – MT, Brazil, Ferrari, Carlos Kusano Bucalen; Institute of Biological and Health Science - Federal University of Mato Grosso – Pontal do Araguaia – MT, Brazil. - Rodovia MT 100, Km 3,5 s/no, Pontal do Araguaia - MT. CEP:78698-000, Correa, Valéria Conde; Environmental Biodiversity Center EcoCerrado Reserve, Araxá, MG-Brazil., França, Eduardo Luzia; Institute of Biological and Health Science - Federal University of Mato Grosso – Pontal do Araguaia – MT, Brazil. - Rodovia MT 100, Km 3,5 s/no, Pontal do Araguaia - MT. CEP:78698-000, Honorio-França, Adenilda Cristina; Institute of Biological and Health Science - Federal University of Mato Grosso – Pontal do Araguaia – MT, Brazil. - Rodovia MT 100, Km 3,5 s/no, Pontal do Araguaia - MT. CEP:78698-000, Maynié, Joanna Conde; Environmental Biodiversity Center EcoCerrado Reserve, Araxá, MG-Brazil., Pereira, Uender Correia Rodrigues; Institute of Biological and Health Science - Federal University of Mato Grosso – Pontal do Araguaia – MT, Brazil. - Rodovia MT 100, Km 3,5 s/no, Pontal do Araguaia - MT. CEP:78698-000   +6 more
core   +1 more source

Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome [PDF]

, 2016
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening disease. These fungi commonly enter their host via inhalation into the lungs where they encounter resident phagocytes, including macrophages and dendritic cells, whose
Chrissy M Leopold Wager, Chrissy M. Leopold Wager, Karen L. Wozniak, Camaron R Hole, Floyd Layton Wormley, Camaron R. Hole, Floyd L. Wormley   +6 more
core   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source

Distinct Spatiotemporal Distribution of Bacterial Toxin-Produced Cellular cAMP Differentially Inhibits Opsonophagocytic Signaling

Toxins, 2019
Myeloid phagocytes have evolved to rapidly recognize invading pathogens and clear them through opsonophagocytic killing. The adenylate cyclase toxin (CyaA) of Bordetella pertussis and the edema toxin (ET) of Bacillus anthracis are both calmodulin ...
Shakir Hasan, Waheed Ur Rahman, Peter Sebo, Radim Osicka   +3 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Genetic ablation of Drosophila phagocytes reveals their contribution to both development and resistance to bacterial infection [PDF]

, 2009
Drosophila phagocytes participate in development and immune responses through their abilities to perform phagocytosis and/or secrete extra-cellular matrix components, antimicrobial peptides, clotting factors and signalling molecules.
Lemaitre, Bruno, Evans, Iwan, Crozatier, Michèle, Leulier, François, Wood, Will, Defaye, Arnaud   +5 more
core   +1 more source

Microglia and infiltrating macrophages in ictogenesis and epileptogenesis

Frontiers in Molecular Neuroscience
Phagocytes maintain homeostasis in a healthy brain. Upon injury, they are essential for repairing damaged tissue, recruiting other immune cells, and releasing cytokines as the first line of defense.
Sonja Bröer, Alberto Pauletti
doaj   +1 more source

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

Advanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li, Di Chang, Jie Yang, Ying Bai, Min Chen, Daoshuang Li, Zuoyu Xu, Jiaxin Yuan, Xiaoxuan Xu, Zhiqi Zhang, Yize Li, Zixin Chen, Jinbing Xie, Zebin Xiao, Shenghong Ju   +14 more
wiley   +1 more source