Results 31 to 40 of about 420,323 (395)
A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells
Scientific Reports, 2021 Phagocytosis of microbial pathogens, dying or dead cells, and cell debris is essential to maintain tissue homeostasis. Impairment of these processes is associated with autoimmunity, developmental defects and toxic protein accumulation.
Benjamin Lindner +6 more
doaj +1 more source
Frontiers in Immunology, 2020 Macrophages are professional phagocytes that are uniquely situated between the innate and adaptive arms of immunity with a high capacity for phagocytosis and proinflammatory cytokine production as well as antigen presentation.
Durga Acharya +3 more
doaj +1 more source
Impaired clearance of early apoptotic cells mediated by inhibitory IgG antibodies in patients with primary Sjögren's syndrome. [PDF]
PLoS ONE, 2014 OBJECTIVES: Deficient efferocytosis (i.e. phagocytic clearance of apoptotic cells) has been frequently reported in systemic lupus erythematosus (SLE).
Menelaos N Manoussakis +3 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 IntroductionKlebsiella pneumoniae (Kp) is a common cause of hospital-acquired pneumonia. Although previous studies have suggested that evasion of phagocytic uptake is a virulence determinant of Kp, few studies have examined phagocytosis sensitivity in ...
Rick van der Geest +19 more
doaj +1 more source
Phosphoinositides and phagocytosis [PDF]
The Journal of Cell Biology, 2001 Phosphoinositide 3 kinases (PI3Ks)**Abbreviation used in this paper: PI3K, phosphoinositide 3 kinase. are known as regulators of phagocytosis. Recent results demonstrate that class I and III PI3Ks act consecutively in phagosome formation and maturation, and that their respective products, phosphatidylinositol 3,4,5-trisphosphate (PI[3,4,5]P3) and ...
David J. Gillooly +2 more
openaire +3 more sources
Scientific Reports, 2021 Following bacterial infection, macrophages produce pro-inflammatory cytokines in response to bacterial cell components, including lipopolysaccharide (LPS) and lipopeptide, and simultaneously phagocytize and digest the invading bacteria.
Takayuki Ueno +2 more
doaj +1 more source
Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome
Journal of Neuroscience, 2020 During adult hippocampal neurogenesis, most newborn cells undergo apoptosis and are rapidly phagocytosed by resident microglia to prevent the spillover of intracellular contents. Here, we propose that phagocytosis is not merely passive corpse removal but
Irune Díaz-Aparicio +19 more
semanticscholar +1 more source
The Phagocytic Code Regulating Phagocytosis of Mammalian Cells
Frontiers in Immunology, 2021 Mammalian phagocytes can phagocytose (i.e. eat) other mammalian cells in the body if they display certain signals, and this phagocytosis plays fundamental roles in development, cell turnover, tissue homeostasis and disease prevention.
Thomas O. J. Cockram +3 more
semanticscholar +1 more source
Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain. [PDF]
, 2000 Phagocytosis and intracellular killing by bovine polymorphonuclear leukocytes (PMN) are important host defence mechanisms against mastitis caused by Staphylococcus aureus. We compared the phagocytosis and overall killing of a non slime-producing (NSP) S.
Barrio, Belén +3 more
core +3 more sources
Phagocytosis in Teleosts. Implications of the New Cells Involved
Biology, 2015 Phagocytosis is the process by which cells engulf some solid particles to form internal vesicles known as phagosomes. Phagocytosis is in fact a specific form of endocytosis involving the vesicular interiorization of particles. Phagocytosis is essentially
María Ángeles Esteban +3 more
doaj +1 more source