Results 151 to 160 of about 50,774 (237)

Sex‐Specific Subcutaneous Adipose Tissue Transcriptome in Obesity: Insights From Monozygotic Twin Pairs Discordant for BMI

Obesity, Volume 34, Issue 2, Page 394-406, February 2026.
ABSTRACT Objective We investigated the impact of sex on the subcutaneous adipose tissue (AT) transcriptome and its obesity‐related adaptations. Methods We studied rare BMI‐discordant monozygotic twin pairs (ΔBMI > 2.5 kg/m2; 21 female, 16 male pairs) to assess how sex affects AT and whole‐body metabolism.
Hanna Haltia, Maheswary Muniandy, Sini Heinonen, Sina Saari, Marcus Alvarez, Antti Hakkarainen, Jesper Lundbom, Juho Kuula, Per‐Henrik Groop, Jaakko Kaprio, Päivi Pajukanta, Kirsi H. Pietiläinen, Birgitta W. van der Kolk   +12 more
wiley   +1 more source

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai, Dongjie Sun, Yanxiao Zhao, Mengtao Zhang, Yifan Wu, Jiabo Ding   +5 more
wiley   +1 more source

The complexity of Rab5 to Rab7 transition guarantees specificity of pathogen subversion mechanisms

Frontiers in Cellular and Infection Microbiology, 2014
Giovanna eMottola, Giovanna eMottola
doaj   +1 more source

The role of hypoxia and complement receptor 2 or toll-like receptor 2 on B1 B cell effector function [PDF]

Master of ScienceDivision of BiologySherry D. FlemingProfessional phagocytes play a critical role in maintaining homeostasis within a host through phagocytic, microbicidal, and inflammatory activity.
Knights, Kaori
core   +1 more source

Research progress on protein tyrosine phosphatase A from Mycobacterium tuberculosis. [PDF]

Front Immunol
Cai Y, Zhang L.
europepmc   +1 more source

Pharmacological inhibition of host pathways enhances macrophage killing of intracellular bacterial pathogens. [PDF]

Microbiol Spectr
Rijal R, Gomer RH.
europepmc   +1 more source

IFN-γ and IL-17 elicit synergistic anti-mycobacterial responses by inhibiting coronin-1A retention. [PDF]

Commun Biol
Park HS, Pham TA, Jiang Z, Choi S, Back YW, Jang IT, Shin KW, Son YJ, Choi HG, Kim HJ.   +9 more
europepmc   +1 more source

Novel amino acid residues in listerolysin O drive phagosome escape and pathogenicity in <i>Listeria monocytogenes</i>. [PDF]

Virulence
Xia J, Feng Y, Xu J, Deng S, Chen M, Han Y, Wang J, Sun J, Rantsiou K, Cocolin LS, Song H, Cheng C.   +11 more
europepmc   +1 more source

Integrated Regulation of Immunity and Nutritional Symbiosis in Deep-Sea Mussels. [PDF]

Mar Drugs
Tame A.
europepmc   +1 more source

Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 1; referees: 2 approved, 2 approved with reservations] [PDF]

, 2016
et al,, Ory, Daniel S
core   +1 more source