Results 181 to 190 of about 32,198 (216)
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The phagosome proteome: insight into phagosome functions.
The Journal of cell biology, 2001Phagosomes are key organelles for the innate ability of macrophages to participate in tissue remodeling, clear apoptotic cells, and restrict the spread of intracellular pathogens. To understand the functions of phagosomes, we initiated the systematic identification of their proteins.
J, Garin +8 more
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A Role for the Phagosome in Cytokine Secretion
Science, 2005Membrane traffic in activated macrophages is required for two critical events in innate immunity: proinflammatory cytokine secretion and phagocytosis of pathogens. We found a joint trafficking pathway linking both actions, which may economize membrane transport and augment the immune response. Tumor necrosis factor α (TNFα) is trafficked from the Golgi
Murray, R. Z. +3 more
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2008
Electron microscopy (EM) is the only technique that can combine sensitive protein-detection methods with detailed information on the substructure of cellular compartments. The purpose of this chapter is to describe some of the methods at the EM level that can be used to analyze the spatial organization of cell organelles with respect to phagosomes or ...
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Electron microscopy (EM) is the only technique that can combine sensitive protein-detection methods with detailed information on the substructure of cellular compartments. The purpose of this chapter is to describe some of the methods at the EM level that can be used to analyze the spatial organization of cell organelles with respect to phagosomes or ...
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Characterization of the Mycobacterium tubercolosis phagosome
Journal of the American College of Cardiology, 1996Mycobacterium tuberculosis parasitizes host macrophages and resides in a phagosome that does not fuse with lysosomes and that resists acidification. Compared with phagosomes containing inert particles, the M. tuberculosis phagosome exhibits maturational arrest: plasma membrane proteins and early endocytic markers persist and there is limited ...
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The Journal of Protozoology, 1985
ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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Inside the phagosome: A bacterial perspective
Immunological Reviews, 2023Mark B Hampton, Nina Dickerhof
exaly
Better Together: Current Insights Into Phagosome-Lysosome Fusion
Frontiers in Immunology, 2021Robin M Yates, Yates Robin M
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RELATIONSHIP BETWEEN PHAGOSOME ACIDIFICATION AND PHAGOSOME‐LYSOSOME FUSION
Biology of the Cell, 1993BOUVIER Gaëlle +4 more
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Phagosome maturation: going through the acid test
Nature Reviews Molecular Cell Biology, 2008Jason M Kinchen +2 more
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