Results 211 to 220 of about 50,774 (237)
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Immunological Reviews, 2023
SummaryPhagocytosis is a fundamental immunobiological process responsible for the removal of harmful particulates. While the number of phagocytic events achieved by a single phagocyte can be remarkable, exceeding hundreds per day, the same phagocytic cells are relatively long‐lived.
Sivakami Mylvaganam, Spencer A. Freeman
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SummaryPhagocytosis is a fundamental immunobiological process responsible for the removal of harmful particulates. While the number of phagocytic events achieved by a single phagocyte can be remarkable, exceeding hundreds per day, the same phagocytic cells are relatively long‐lived.
Sivakami Mylvaganam, Spencer A. Freeman
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Intracellular Transformation of Phagosomes
Biology Bulletin, 2004The transformation of nascent phagosomes into forms capable of interacting with antimicrobial organelles of phagocytes, peroxisomes, depends on certain interactions between phagosomes and other vacuolar organelles. Phagosomes repeatedly interact with early and late endosomes through temporary contacts, which allows them to gain and lose complex sets of
P G, But +3 more
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Single-phagosome imaging reveals that homotypic fusion impairs phagosome degradative function
Biophysical Journal, 2022Immune cells degrade internalized pathogens in vesicle compartments called phagosomes. Many intracellular bacteria induce homotypic phagosome fusion to survive in host cells, but the fusion interaction between phagosomes and its consequence for phagosome function have scarcely been studied.
Yanqi Yu +3 more
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Actin‐based phagosome motility
Cell Motility, 2002AbstractDespite abundant evidence of actin's involvement at the particle internalization stage of phagocytosis, little is known about whether phagosomes undergo the same type of actin‐based motility as observed with endocytic vesicles or such intracellular pathogens as Listeria and Shigella.
Fangliang, Zhang +2 more
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Measurement of phagosome-lysosome fusion and phagosomal pH
1994Publisher Summary Phagosome–lysosome fusion has been assessed by several different methods. Most of these strategies involve either the identification of endogenous lysosomal markers in organelles containing ingested organisms or the colocalization of the phagocytosed organism with an exogenous marker endocytosed by the cell and sequestered within ...
T H, Steinberg, J A, Swanson
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Salmonella redirects phagosomal maturation
Current Opinion in Microbiology, 2004Following invasion of host cells, Salmonella occupies an intracellular vacuole that superficially resembles a phagosome. However, unlike bona fide phagosomes that undergo a maturation process to become microbicidal phago-lysosomes, Salmonella avoid killing by arresting and diverting the maturation program of the invasion vacuole. As a result of this re-
John H, Brumell, Sergio, Grinstein
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Phagosome dynamics and function
BioEssays, 2000Phagocytosis of microorganisms and other particles is mediated most efficiently by receptors such as Fc-receptors (FcR) and complement-receptors (C3R). Interaction between these receptors and ligands on the particle results in signal transduction events that lead to actin polymerisation and phagosome formation. The phagosome then undergoes a maturation
T E, Tjelle, T, Lovdal, T, Berg
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2008
Autophagy and phagocytosis are evolutionarily ancient processes functioning in capture and digestion of material found in the cellular interior and exterior, respectively. In their most primordial form, both processes are involved in cellular metabolism and feeding, supplying cells with externally obtained particulate nutrients or using portions of ...
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Autophagy and phagocytosis are evolutionarily ancient processes functioning in capture and digestion of material found in the cellular interior and exterior, respectively. In their most primordial form, both processes are involved in cellular metabolism and feeding, supplying cells with externally obtained particulate nutrients or using portions of ...
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The Journal of Protozoology, 1985
ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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ABSTRACTThis study examines the relationship between phagosome acidification and phagosome‐lysosome fusion events using phagocytized Glugea hertwigi spores. The incidence of lysosome fusion with Glugea spores in phagosomes of mouse peritoneal macrophages and of Tetrahymena was monitored using colloidal gold and acridine orange as labels for secondary ...
E, Weidner, L D, Sibley
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Large-Scale Phagosome Preparation
2009Phagocytosis is the process by which cells engulf and destroy large particles such as pathogens or apoptotic cells. In this way, macrophages play a pivotal role in the resolution of microbial infections. However, many microorganisms have evolved efficient strategies to preempt the weaponry of macrophages.
Vinet, Adrien F., Descoteaux, Albert
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