Results 121 to 130 of about 36,298 (238)

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

A Drosophila Model to Image Phagosome Maturation

open access: yesCells, 2013
Phagocytosis involves the internalization of extracellular material by invagination of the plasma membrane to form intracellular vesicles called phagosomes, which have functions that include pathogen degradation.
Douglas A. Brooks   +3 more
doaj   +1 more source

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

open access: yesMolecular Microbiology, EarlyView.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç   +4 more
wiley   +1 more source

The WD40 domain of ATG16L1 is required for its non-canonical role in lipidation of LC3 at single membranes [PDF]

open access: yes, 2018
A hallmark of macroautophagy is the covalent lipidation of LC3 and insertion into the double-membrane phagophore, which is driven by the ATG16L1/ATG5-ATG12 complex.
Elise Jacquin   +11 more
core   +2 more sources

‘Candidatus Liberibacter Asiaticus’ Effector SECP8 Subverts Salicylic Acid‐Mediated Citrus Immunity via a Two‐Pronged Impairment of CsTCP15 Dimerization

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Citrus Huanglongbing (HLB), a devastating disease caused by the unculturable bacterium ‘Candidatus Liberibacter asiaticus’ (CLas), poses a severe threat to global citrus production. CLas secretes effectors to suppress host immune responses and facilitate its colonisation. Previously, the CLas effector SECP8 (CLIBASIA_05330) has been identified
Mingyue Qin   +8 more
wiley   +1 more source

The unusual microtubule polarity in teleost retinal pigment epithelial cells. [PDF]

open access: yes, 1988
In cells of the teleost retinal pigment epithelium (RPE), melanin granules disperse into the RPE cells long apical projections in response to light onset, and aggregate toward the base of the RPE cell in response to dark onset.
BURNSIDE, Beth, Troutt, L
core   +1 more source

Correlative light and immuno-electron microscopy of retinal tissue cryostat sections [PDF]

open access: yes, 2018
Correlative light-electron microscopy (CLEM) is a powerful technique allowing localisation of specific macromolecules within fluorescence microscopy (FM) images to be mapped onto corresponding high-resolution electron microscopy (EM) images.
Burgoyne, T   +4 more
core   +1 more source

Cryptococcus neoformans escape From Dictyostelium amoeba by both WASH-mediated constitutive exocytosis and vomocytosis [PDF]

open access: yes, 2018
Cryptococcus neoformans is an environmental yeast that can cause opportunistic infections in humans. As infecting animals does not form part of its normal life-cycle, it has been proposed that the virulence traits that allow cryptococci to resist immune ...
Andrews, A.   +5 more
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

open access: yesVeterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Delay of phagosome maturation by a mycobacterial lipid is reversed by nitric oxide.

open access: yes, 2008
Mycobacterium tuberculosis is a facultative intracellular pathogen that inhibits phagosome maturation in macrophages thereby securing survival and growth.
Axelrod, Sofia   +7 more
core   +1 more source

Home - About - Disclaimer - Privacy